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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAPTM4A
All Species:
20.91
Human Site:
Y140
Identified Species:
46
UniProt:
Q15012
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15012
NP_055528.1
233
26801
Y140
Y
L
P
R
I
K
E
Y
L
D
Q
L
P
D
F
Chimpanzee
Pan troglodytes
XP_001138597
223
25623
P135
K
E
Y
L
D
Q
L
P
D
F
P
Y
K
D
D
Rhesus Macaque
Macaca mulatta
XP_001094983
233
26769
Y140
Y
L
P
R
I
K
E
Y
L
D
Q
L
P
D
F
Dog
Lupus familis
XP_532277
393
42843
Y299
Y
P
N
S
I
Q
E
Y
I
R
Q
L
P
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q60961
233
26839
Y140
Y
L
P
R
I
K
E
Y
L
D
Q
L
P
D
F
Rat
Rattus norvegicus
Q6P501
233
26765
Y140
Y
L
P
R
I
K
E
Y
L
D
Q
L
P
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505310
230
26394
Q140
R
I
K
D
Y
L
D
Q
L
P
D
F
P
Y
K
Chicken
Gallus gallus
Q5ZML7
229
26256
L140
I
K
D
Y
L
D
Q
L
P
D
F
P
Y
K
D
Frog
Xenopus laevis
NP_001085774
231
26214
L140
I
K
E
Y
L
E
Q
L
P
H
F
P
Y
K
E
Zebra Danio
Brachydanio rerio
NP_999850
238
27236
Y145
Y
L
P
R
I
K
D
Y
L
D
Q
L
P
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724705
432
47591
I184
Y
L
Q
A
I
H
S
I
I
A
E
S
H
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
99.1
26.7
N.A.
97
97.8
N.A.
89.6
87.1
73.8
76
N.A.
21.7
N.A.
N.A.
N.A.
Protein Similarity:
100
95.7
100
40.2
N.A.
98.7
99.5
N.A.
97.4
95.2
89.2
87.8
N.A.
33
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
46.6
N.A.
100
100
N.A.
13.3
6.6
0
93.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
60
N.A.
100
100
N.A.
26.6
20
20
100
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
10
10
19
0
10
55
10
0
0
55
19
% D
% Glu:
0
10
10
0
0
10
46
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
19
10
0
0
46
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
10
0
0
10
0
0
% H
% Ile:
19
10
0
0
64
0
0
10
19
0
0
0
0
0
0
% I
% Lys:
10
19
10
0
0
46
0
0
0
0
0
0
10
19
10
% K
% Leu:
0
55
0
10
19
10
10
19
55
0
0
55
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
10
46
0
0
0
0
10
19
10
10
19
64
10
0
% P
% Gln:
0
0
10
0
0
19
19
10
0
0
55
0
0
0
0
% Q
% Arg:
10
0
0
46
0
0
0
0
0
10
0
0
0
10
0
% R
% Ser:
0
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
64
0
10
19
10
0
0
55
0
0
0
10
19
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _