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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEPACAM
All Species:
9.09
Human Site:
T295
Identified Species:
28.57
UniProt:
Q14CZ8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14CZ8
NP_689935.2
416
46026
T295
R
L
K
P
E
A
D
T
L
P
R
S
G
E
Q
Chimpanzee
Pan troglodytes
XP_522240
416
45990
T295
R
L
K
P
E
A
D
T
L
P
R
S
G
E
Q
Rhesus Macaque
Macaca mulatta
XP_001106985
546
60851
T425
R
L
K
P
E
A
D
T
L
P
R
S
G
D
Q
Dog
Lupus familis
XP_852267
418
45887
A295
D
D
R
L
K
P
E
A
D
T
L
P
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q640R3
418
46348
A295
D
D
R
L
K
S
E
A
D
T
L
P
R
S
G
Rat
Rattus norvegicus
Q9JHY1
300
32351
F183
D
A
K
K
T
R
A
F
I
N
S
S
Y
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425793
386
42020
P268
N
L
C
S
L
S
R
P
K
Q
Q
A
E
P
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018526
422
46573
R295
V
V
D
I
V
P
A
R
N
Y
H
N
R
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
73.4
93.5
N.A.
94.2
23
N.A.
N.A.
66.8
N.A.
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
75
96.4
N.A.
96.6
35.8
N.A.
N.A.
77.1
N.A.
68.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
0
13.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
26.6
20
N.A.
N.A.
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
38
25
25
0
0
0
13
0
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
38
25
13
0
0
0
38
0
25
0
0
0
0
13
0
% D
% Glu:
0
0
0
0
38
0
25
0
0
0
0
0
13
25
0
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
38
13
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
13
% I
% Lys:
0
0
50
13
25
0
0
0
13
0
0
0
0
0
0
% K
% Leu:
0
50
0
25
13
0
0
0
38
0
25
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
13
13
0
13
0
0
13
% N
% Pro:
0
0
0
38
0
25
0
13
0
38
0
25
0
13
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
13
13
0
0
0
38
% Q
% Arg:
38
0
25
0
0
13
13
13
0
0
38
0
38
13
0
% R
% Ser:
0
0
0
13
0
25
0
0
0
0
13
50
0
13
0
% S
% Thr:
0
0
0
0
13
0
0
38
0
25
0
0
0
13
0
% T
% Val:
13
13
0
0
13
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _