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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM180
All Species:
13.64
Human Site:
S180
Identified Species:
37.5
UniProt:
Q14CX5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14CX5
NP_079065.2
517
57381
S180
G
S
L
S
V
F
A
S
Y
A
F
W
N
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112663
517
57617
S180
G
S
L
S
V
F
A
S
Y
A
F
W
N
K
E
Dog
Lupus familis
XP_543992
517
57285
S180
G
S
L
S
V
F
A
S
Y
A
F
W
N
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDE8
519
57879
S180
G
S
L
S
V
F
A
S
Y
A
F
W
N
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511850
512
58163
L177
L
G
S
L
S
V
F
L
S
Y
A
V
W
N
K
Chicken
Gallus gallus
Q5ZKJ5
509
58057
M177
I
G
S
L
S
V
F
M
S
Y
A
V
W
N
K
Frog
Xenopus laevis
NP_001088248
509
57748
A177
I
G
S
L
S
V
F
A
S
Y
T
V
W
N
K
Zebra Danio
Brachydanio rerio
NP_001008654
504
56854
V173
L
F
S
A
I
G
S
V
S
V
F
L
S
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491478
468
53034
R140
T
Q
N
Q
S
L
I
R
V
K
A
L
K
Y
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.2
91.4
N.A.
89
N.A.
N.A.
73.8
71.7
66.5
68.8
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
N.A.
98.6
94.3
N.A.
92.6
N.A.
N.A.
82.4
82.2
79.1
80.2
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
0
0
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
6.6
6.6
13.3
33.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
45
12
0
45
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% E
% Phe:
0
12
0
0
0
45
34
0
0
0
56
0
0
0
0
% F
% Gly:
45
34
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
23
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
0
12
45
34
% K
% Leu:
23
0
45
34
0
12
0
12
0
0
0
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
45
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
45
45
45
45
0
12
45
45
0
0
0
12
0
23
% S
% Thr:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
45
34
0
12
12
12
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
45
34
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
45
34
0
0
0
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _