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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP19
All Species:
28.18
Human Site:
Y251
Identified Species:
68.89
UniProt:
Q14CB8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14CB8
NP_116289.4
494
55756
Y251
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Chimpanzee
Pan troglodytes
XP_001161248
493
55609
Y251
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Rhesus Macaque
Macaca mulatta
XP_001101897
494
55652
Y251
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Dog
Lupus familis
XP_534979
517
58808
Y251
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH3
494
55716
Y251
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Rat
Rattus norvegicus
XP_001054615
479
54201
F232
I
E
A
L
Q
L
L
F
L
I
L
P
P
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505449
583
65045
D302
T
Q
K
R
N
R
V
D
S
C
S
H
Q
E
E
Chicken
Gallus gallus
Q5F3G0
495
55431
Y247
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Frog
Xenopus laevis
Q6INE5
507
57385
Y248
K
L
L
L
D
L
L
Y
Q
T
A
R
K
Q
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199994
277
31567
T42
H
V
L
D
F
S
G
T
D
G
L
G
Q
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
90.7
N.A.
87.8
83.8
N.A.
58.8
72.9
66
N.A.
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
99.8
98.5
92.4
N.A.
93.1
88.8
N.A.
65.8
81.6
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
0
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
40
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
70
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
70
0
0
10
10
0
0
0
0
0
70
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
70
0
10
0
0
0
0
0
0
0
0
60
70
0
0
% K
% Leu:
0
70
80
80
0
80
80
0
10
0
20
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
10
0
0
10
0
0
0
70
0
0
0
20
70
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
10
0
70
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _