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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP19
All Species:
14.24
Human Site:
T474
Identified Species:
34.81
UniProt:
Q14CB8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14CB8
NP_116289.4
494
55756
T474
F
S
G
S
P
A
V
T
M
T
P
T
R
L
K
Chimpanzee
Pan troglodytes
XP_001161248
493
55609
M474
S
G
S
P
A
V
T
M
T
P
T
R
L
K
W
Rhesus Macaque
Macaca mulatta
XP_001101897
494
55652
T474
F
S
G
S
P
A
V
T
M
T
P
T
R
L
K
Dog
Lupus familis
XP_534979
517
58808
T474
F
S
G
S
P
A
V
T
M
T
P
T
R
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH3
494
55716
T474
F
S
G
S
P
A
G
T
V
T
P
T
R
L
K
Rat
Rattus norvegicus
XP_001054615
479
54201
E461
E
L
K
K
A
S
K
E
N
M
N
L
D
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505449
583
65045
I566
L
T
L
N
N
N
N
I
T
T
I
P
V
S
S
Chicken
Gallus gallus
Q5F3G0
495
55431
L469
A
H
M
S
Q
G
K
L
K
S
L
E
G
Q
K
Frog
Xenopus laevis
Q6INE5
507
57385
R475
S
P
A
V
Y
F
T
R
A
K
L
K
L
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199994
277
31567
S261
W
P
R
F
V
S
K
S
F
R
V
L
A
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
90.7
N.A.
87.8
83.8
N.A.
58.8
72.9
66
N.A.
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
99.8
98.5
92.4
N.A.
93.1
88.8
N.A.
65.8
81.6
78.6
N.A.
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
0
100
100
N.A.
86.6
0
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
93.3
6.6
N.A.
20
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
20
40
0
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
10
% E
% Phe:
40
0
0
10
0
10
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
10
40
0
0
10
10
0
0
0
0
0
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
10
0
0
30
0
10
10
0
10
0
10
50
% K
% Leu:
10
10
10
0
0
0
0
10
0
0
20
20
20
40
10
% L
% Met:
0
0
10
0
0
0
0
10
30
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
10
10
0
10
0
10
0
0
0
0
% N
% Pro:
0
20
0
10
40
0
0
0
0
10
40
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
10
0
10
0
10
40
10
0
% R
% Ser:
20
40
10
50
0
20
0
10
0
10
0
0
0
30
10
% S
% Thr:
0
10
0
0
0
0
20
40
20
50
10
40
0
0
0
% T
% Val:
0
0
0
10
10
10
30
0
10
0
10
0
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _