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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
26.67
Human Site:
Y748
Identified Species:
58.67
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
Y748
S
S
L
R
V
L
V
Y
Q
G
V
K
K
D
G
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
Y748
S
S
L
R
V
L
V
Y
Q
G
V
K
K
D
G
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
Y748
S
S
L
R
V
L
V
Y
Q
G
V
K
K
D
G
Dog
Lupus familis
XP_533438
1685
193077
Y750
S
S
L
R
V
L
V
Y
Q
G
V
K
K
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
Y739
S
S
L
R
V
L
V
Y
Q
G
V
K
K
H
G
Rat
Rattus norvegicus
NP_001100940
1701
194686
Y746
S
S
L
R
V
L
V
Y
Q
G
V
K
K
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
W230
F
L
G
V
D
P
Y
W
V
K
H
W
W
D
Q
Chicken
Gallus gallus
XP_419651
1681
192161
Y747
S
S
L
R
V
L
V
Y
Q
G
V
K
K
H
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
W458
M
L
P
A
I
N
R
W
A
V
T
G
T
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
A509
A
T
L
I
V
C
P
A
P
I
L
P
Q
W
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
L742
A
R
E
V
I
E
T
L
K
R
D
I
L
K
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
6.6
93.3
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
93.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
0
0
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
10
0
0
55
10
% D
% Glu:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
64
0
10
0
0
64
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
19
10
% H
% Ile:
0
0
0
10
19
0
0
0
0
10
0
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
0
64
64
10
0
% K
% Leu:
0
19
73
0
0
64
0
10
0
0
10
0
10
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
10
10
0
10
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
64
0
0
0
10
0
10
% Q
% Arg:
0
10
0
64
0
0
10
0
0
10
0
0
0
0
10
% R
% Ser:
64
64
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
10
0
10
0
0
% T
% Val:
0
0
0
19
73
0
64
0
10
10
64
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
19
0
0
0
10
10
10
0
% W
% Tyr:
0
0
0
0
0
0
10
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _