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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
20.61
Human Site:
Y106
Identified Species:
45.33
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
Y106
L
N
I
V
I
S
P
Y
H
F
D
N
S
W
K
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
Y106
L
N
I
V
I
S
P
Y
H
F
D
N
S
W
K
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
Y106
L
N
I
V
I
S
P
Y
H
F
D
N
S
W
K
Dog
Lupus familis
XP_533438
1685
193077
Y105
L
N
I
V
I
S
P
Y
H
F
D
N
S
W
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
Y98
L
N
V
T
V
S
P
Y
R
V
D
N
S
W
K
Rat
Rattus norvegicus
NP_001100940
1701
194686
H97
L
N
V
T
I
S
P
H
P
S
D
D
S
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
Chicken
Gallus gallus
XP_419651
1681
192161
Y108
L
N
I
V
V
L
P
Y
C
A
D
G
S
W
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
D98
I
E
V
D
H
D
L
D
C
S
L
R
F
R
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
66.6
60
N.A.
0
66.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
0
73.3
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
10
0
0
64
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
37
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
10
37
0
0
0
0
0
0
% H
% Ile:
10
0
46
0
46
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% K
% Leu:
64
0
0
0
0
10
10
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
64
0
0
0
0
0
0
0
0
0
46
0
0
0
% N
% Pro:
0
0
0
0
0
0
64
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
10
0
10
0
% R
% Ser:
0
0
0
0
0
55
0
0
0
19
0
0
64
0
0
% S
% Thr:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
28
46
19
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _