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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
16.36
Human Site:
T88
Identified Species:
36
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
T88
K
P
I
E
K
E
E
T
V
G
I
F
S
P
L
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
T88
K
P
I
E
K
E
E
T
V
G
I
F
S
P
L
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
T88
K
P
I
E
K
E
E
T
V
G
I
F
S
P
L
Dog
Lupus familis
XP_533438
1685
193077
T87
K
S
N
D
K
E
E
T
C
G
T
F
S
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
A80
E
T
V
S
V
L
E
A
T
E
E
E
T
R
L
Rat
Rattus norvegicus
NP_001100940
1701
194686
S79
E
S
V
S
I
L
N
S
T
E
K
E
T
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
Chicken
Gallus gallus
XP_419651
1681
192161
S90
T
A
N
D
G
E
D
S
N
S
N
S
T
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
R80
T
N
F
S
V
R
E
R
V
G
S
S
S
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
13.3
13.3
N.A.
0
13.3
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
33.3
40
N.A.
0
46.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
0
28
0
46
55
0
0
19
10
19
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
37
0
0
10
% F
% Gly:
0
0
0
0
10
0
0
0
0
46
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
28
0
10
0
0
0
0
0
28
0
0
0
0
% I
% Lys:
37
0
0
0
37
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
19
0
0
0
10
0
10
0
10
0
0
0
0
% N
% Pro:
0
28
0
0
0
0
0
0
0
0
0
0
0
55
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% R
% Ser:
0
19
0
28
0
0
0
19
0
10
10
19
46
0
0
% S
% Thr:
19
10
0
0
0
0
0
37
19
0
10
0
28
10
0
% T
% Val:
0
0
19
0
19
0
0
0
37
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _