KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
13.94
Human Site:
T584
Identified Species:
30.67
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
T584
R
K
K
L
V
P
S
T
K
K
G
K
S
Q
P
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
T584
R
K
K
L
V
P
S
T
K
K
G
K
R
Q
P
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
T584
R
K
K
P
I
P
S
T
K
K
G
K
S
Q
P
Dog
Lupus familis
XP_533438
1685
193077
T586
R
K
K
P
V
T
S
T
K
K
G
K
G
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
L575
K
L
K
K
P
A
L
L
T
K
K
G
K
G
Q
Rat
Rattus norvegicus
NP_001100940
1701
194686
L582
L
K
K
K
P
V
L
L
T
K
K
E
K
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
T85
M
L
R
W
K
S
E
T
P
V
F
L
P
T
V
Chicken
Gallus gallus
XP_419651
1681
192161
N586
N
E
N
S
M
E
E
N
N
I
Q
K
A
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
L313
T
I
S
E
K
S
D
L
P
H
L
C
P
S
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
I364
P
P
Y
V
S
G
G
I
L
A
D
E
M
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
T596
P
V
I
P
T
P
L
T
R
I
F
W
W
R
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
80
N.A.
13.3
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
80
N.A.
20
26.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
10
0
10
19
0
0
0
0
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
37
10
10
28
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
0
0
10
0
19
0
0
0
0
10
% I
% Lys:
10
46
55
19
19
0
0
0
37
55
19
46
19
0
0
% K
% Leu:
10
19
0
19
0
0
28
28
10
0
10
10
0
0
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
19
10
0
28
19
37
0
0
19
0
0
0
19
0
37
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
37
19
% Q
% Arg:
37
0
10
0
0
0
0
0
10
0
0
0
10
10
0
% R
% Ser:
0
0
10
10
10
19
37
0
0
0
0
0
19
10
0
% S
% Thr:
10
0
0
0
10
10
0
55
19
0
0
0
0
10
0
% T
% Val:
0
10
0
10
28
10
0
0
0
10
0
0
0
0
19
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _