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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
15.76
Human Site:
S621
Identified Species:
34.67
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
S621
M
S
K
S
T
C
I
S
E
F
N
Q
E
H
E
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
S621
M
S
K
S
T
C
I
S
E
F
N
Q
E
H
E
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
S621
I
S
K
S
T
C
I
S
E
F
N
Q
E
N
E
Dog
Lupus familis
XP_533438
1685
193077
F623
T
S
K
S
A
C
I
F
E
G
K
Q
E
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
S612
V
S
E
N
T
C
V
S
E
D
K
Q
T
Q
E
Rat
Rattus norvegicus
NP_001100940
1701
194686
S619
V
S
E
S
T
C
V
S
E
N
R
Q
I
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
A122
F
L
Q
P
H
M
L
A
E
Q
D
I
V
I
T
Chicken
Gallus gallus
XP_419651
1681
192161
D623
D
V
S
K
S
T
T
D
V
Q
Q
E
M
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
F350
N
A
I
K
M
Q
W
F
E
E
I
H
K
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
N401
V
V
A
P
T
W
Q
N
T
G
N
Q
K
I
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
I633
Y
T
K
H
R
W
C
I
T
G
T
P
I
Q
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
60
N.A.
46.6
46.6
N.A.
6.6
0
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
60
N.A.
73.3
73.3
N.A.
33.3
13.3
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
55
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
10
10
0
0
0
10
% D
% Glu:
0
0
19
0
0
0
0
0
73
10
0
10
37
0
37
% E
% Phe:
10
0
0
0
0
0
0
19
0
28
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
10
0
37
0
% H
% Ile:
10
0
10
0
0
0
37
10
0
0
10
10
19
19
10
% I
% Lys:
0
0
46
19
0
0
0
0
0
0
19
0
19
0
0
% K
% Leu:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
19
0
0
0
10
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
10
0
0
0
10
0
10
37
0
0
10
10
% N
% Pro:
0
0
0
19
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
10
0
0
10
10
0
0
19
10
64
0
28
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
19
% R
% Ser:
0
55
10
46
10
0
0
46
0
0
0
0
0
0
0
% S
% Thr:
10
10
0
0
55
10
10
0
19
0
10
0
10
0
10
% T
% Val:
28
19
0
0
0
0
19
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _