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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHPRH
All Species:
23.33
Human Site:
S1225
Identified Species:
51.33
UniProt:
Q149N8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q149N8
NP_001036148.1
1683
193079
S1225
P
S
R
N
V
I
E
S
A
T
V
C
H
L
R
Chimpanzee
Pan troglodytes
XP_001172976
1683
193077
S1225
P
S
R
N
V
I
E
S
A
T
V
C
H
L
R
Rhesus Macaque
Macaca mulatta
XP_001086512
1683
193033
S1225
P
S
R
N
V
I
E
S
A
T
V
C
H
L
R
Dog
Lupus familis
XP_533438
1685
193077
S1227
P
S
R
N
V
I
E
S
A
T
I
C
H
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPQ3
1674
191472
S1216
P
S
R
E
V
I
E
S
A
T
V
C
H
L
R
Rat
Rattus norvegicus
NP_001100940
1701
194686
S1243
P
S
R
D
V
I
E
S
A
T
V
C
H
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506895
1042
119725
R648
D
R
L
P
T
T
S
R
G
L
W
A
A
S
E
Chicken
Gallus gallus
XP_419651
1681
192161
A1223
P
S
K
E
V
I
E
A
A
T
I
C
H
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648034
1270
148040
R877
P
K
K
H
R
Y
C
R
L
C
L
I
R
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002329202
1320
149464
S927
D
A
K
K
Q
K
A
S
G
E
D
S
D
F
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181609
1664
188054
D1177
P
T
K
R
N
A
G
D
I
V
V
L
S
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98
92.5
N.A.
86
84.6
N.A.
52.7
72
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
95.7
N.A.
91.8
90.7
N.A.
56.9
82.2
N.A.
N.A.
N.A.
42.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
73.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
0
93.3
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
37.7
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
10
64
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
64
0
0
0
% C
% Asp:
19
0
0
10
0
0
0
10
0
0
10
0
10
10
0
% D
% Glu:
0
0
0
19
0
0
64
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
10
0
19
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
64
0
0
% H
% Ile:
0
0
0
0
0
64
0
0
10
0
19
10
0
0
0
% I
% Lys:
0
10
37
10
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
0
0
0
0
0
10
10
10
10
0
64
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
37
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
82
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
55
10
10
0
0
19
0
0
0
0
10
0
64
% R
% Ser:
0
64
0
0
0
0
10
64
0
0
0
10
10
10
19
% S
% Thr:
0
10
0
0
10
10
0
0
0
64
0
0
0
0
10
% T
% Val:
0
0
0
0
64
0
0
0
0
10
55
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _