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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNB1
All Species:
41.21
Human Site:
Y757
Identified Species:
82.42
UniProt:
Q14974
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14974
NP_002256.2
876
97170
Y757
S
D
Y
D
M
V
D
Y
L
N
E
L
R
E
S
Chimpanzee
Pan troglodytes
XP_511927
918
101671
Y799
S
D
Y
D
M
V
D
Y
L
N
E
L
R
E
S
Rhesus Macaque
Macaca mulatta
XP_001082833
1044
114674
Y925
S
D
Y
D
M
V
D
Y
L
N
E
L
R
E
S
Dog
Lupus familis
XP_548162
876
97209
Y757
S
D
Y
D
M
V
D
Y
L
N
E
L
R
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P70168
876
97134
Y757
S
D
F
D
M
V
D
Y
L
N
E
L
R
E
S
Rat
Rattus norvegicus
P52296
875
97106
Y756
S
D
F
D
M
V
D
Y
L
N
E
L
R
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P52297
260
28799
V165
G
H
Q
N
N
L
D
V
V
M
A
S
L
L
X
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18388
884
98677
Y763
N
N
F
D
M
N
E
Y
I
N
E
L
R
E
S
Honey Bee
Apis mellifera
XP_393927
894
99270
Y764
S
D
Y
D
M
I
D
Y
L
N
E
L
R
E
G
Nematode Worm
Caenorhab. elegans
NP_491477
896
98740
Y769
N
D
D
D
Q
V
D
Y
V
D
R
L
R
E
A
Sea Urchin
Strong. purpuratus
XP_781574
862
96235
Y739
T
D
F
D
M
I
D
Y
L
N
D
L
R
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06142
861
94757
Y746
G
T
L
E
A
L
D
Y
Q
I
K
V
L
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
82.6
99.4
N.A.
99
98.5
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
61
66.8
48.2
67.2
Protein Similarity:
100
93.7
83.6
99.6
N.A.
99.7
99.1
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
76.4
79.4
65.9
80.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
60
86.6
53.3
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
93.3
93.3
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
9
84
0
0
92
0
0
9
9
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
9
0
0
0
67
0
0
92
0
% E
% Phe:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
0
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
9
0
0
17
0
0
67
0
0
84
17
9
0
% L
% Met:
0
0
0
0
75
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
17
9
0
9
9
9
0
0
0
75
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
84
0
0
% R
% Ser:
59
0
0
0
0
0
0
0
0
0
0
9
0
0
50
% S
% Thr:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
59
0
9
17
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
42
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _