KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNB1
All Species:
42.73
Human Site:
Y249
Identified Species:
85.45
UniProt:
Q14974
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14974
NP_002256.2
876
97170
Y249
V
K
I
M
S
L
Y
Y
Q
Y
M
E
T
Y
M
Chimpanzee
Pan troglodytes
XP_511927
918
101671
Y291
V
K
I
M
S
L
Y
Y
Q
Y
M
E
T
Y
M
Rhesus Macaque
Macaca mulatta
XP_001082833
1044
114674
Y417
V
K
I
M
S
L
Y
Y
Q
Y
M
E
T
Y
M
Dog
Lupus familis
XP_548162
876
97209
Y249
V
K
I
M
S
L
Y
Y
Q
Y
M
E
T
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
P70168
876
97134
Y249
V
K
I
M
S
L
Y
Y
Q
Y
M
E
T
Y
M
Rat
Rattus norvegicus
P52296
875
97106
Y248
V
K
I
M
S
L
Y
Y
Q
Y
M
E
T
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P52297
260
28799
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18388
884
98677
Y255
V
K
I
M
T
L
Y
Y
Q
Y
M
E
P
Y
M
Honey Bee
Apis mellifera
XP_393927
894
99270
Y256
V
K
I
M
S
L
Y
Y
Q
Y
M
E
P
Y
M
Nematode Worm
Caenorhab. elegans
NP_491477
896
98740
Y255
V
R
I
M
Q
L
Y
Y
E
H
M
L
S
Y
M
Sea Urchin
Strong. purpuratus
XP_781574
862
96235
Y230
V
K
I
M
S
L
Y
Y
V
H
M
E
D
Y
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06142
861
94757
Y256
C
K
I
M
S
L
Y
Y
T
F
M
K
P
Y
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
82.6
99.4
N.A.
99
98.5
N.A.
N.A.
N.A.
23.8
N.A.
N.A.
61
66.8
48.2
67.2
Protein Similarity:
100
93.7
83.6
99.6
N.A.
99.7
99.1
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
76.4
79.4
65.9
80.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
0
N.A.
N.A.
86.6
93.3
60
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
0
N.A.
N.A.
93.3
93.3
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
75
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
84
0
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
0
0
0
92
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
92
0
0
0
0
0
0
92
0
0
0
92
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
67
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
75
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
9
0
0
0
50
0
0
% T
% Val:
84
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
92
92
0
67
0
0
0
92
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _