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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASP1 All Species: 12.73
Human Site: Y186 Identified Species: 21.54
UniProt: Q14847 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14847 NP_006139.1 261 29717 Y186 V A Q S Y G G Y K E P A A P V
Chimpanzee Pan troglodytes XP_511445 391 42950 Y316 V A Q S Y G G Y K E P A A P V
Rhesus Macaque Macaca mulatta XP_001085111 261 29741 Y186 V A Q S Y G G Y K E P A A P V
Dog Lupus familis XP_851714 257 29048 G182 Q V A Q S Y G G Y K E P A A P
Cat Felis silvestris
Mouse Mus musculus Q61792 263 29976 G186 Q Q M T S S Y G G Y K E P A A
Rat Rattus norvegicus Q99MZ8 263 29952 G186 Q Q V T P S Y G G Y K E P A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516545 118 13511 Y44 M T L N M K N Y K G Y E K K P
Chicken Gallus gallus Q01406 563 63311 R398 Q E Q E E A R R K L E E Q A K
Frog Xenopus laevis Q6GM14 376 42749 Y300 A T E N Q N I Y E D T P Q E D
Zebra Danio Brachydanio rerio NP_997801 234 26681 Y160 A A S Q N Y H Y E P E P V R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7C3 657 74228 Q186 Q Q Q Q L Q H Q Q Q Q Q Y Q Q
Honey Bee Apis mellifera XP_001121584 320 35562 D186 P G R I A D Y D P L S E A R P
Nematode Worm Caenorhab. elegans P34416 335 37006 K188 A V S P T P Q K S I G S I A D
Sea Urchin Strong. purpuratus XP_797085 249 27176 Q175 Q P A A P V Q Q P P P Q Q L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.7 98.4 94.6 N.A. 95.4 96.1 N.A. 41.7 21.3 21.8 68.5 N.A. 23.1 42.1 37.3 50.1
Protein Similarity: 100 66.7 99.2 95.7 N.A. 97.3 97.3 N.A. 43.6 30.5 38 75.4 N.A. 30.4 53.4 51 60.5
P-Site Identity: 100 100 100 13.3 N.A. 0 0 N.A. 13.3 13.3 6.6 13.3 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 100 100 20 N.A. 6.6 6.6 N.A. 26.6 13.3 33.3 20 N.A. 20 13.3 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 29 15 8 8 8 0 0 0 0 0 22 36 36 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 0 8 0 0 0 0 15 % D
% Glu: 0 8 8 8 8 0 0 0 15 22 22 36 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 22 29 22 15 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 8 0 8 36 8 15 0 8 8 8 % K
% Leu: 0 0 8 0 8 0 0 0 0 15 0 0 0 8 0 % L
% Met: 8 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 8 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 15 8 0 0 15 15 29 22 15 22 29 % P
% Gln: 43 22 36 22 8 8 15 15 8 8 8 15 22 8 8 % Q
% Arg: 0 0 8 0 0 0 8 8 0 0 0 0 0 15 0 % R
% Ser: 0 0 15 22 15 15 0 0 8 0 8 8 0 0 8 % S
% Thr: 0 15 0 15 8 0 0 0 0 0 8 0 0 0 0 % T
% Val: 22 15 8 0 0 8 0 0 0 0 0 0 8 0 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 22 15 22 43 8 15 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _