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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASP1
All Species:
11.21
Human Site:
S198
Identified Species:
18.97
UniProt:
Q14847
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14847
NP_006139.1
261
29717
S198
A
P
V
S
I
Q
R
S
A
P
G
G
G
G
K
Chimpanzee
Pan troglodytes
XP_511445
391
42950
S328
A
P
V
S
I
Q
R
S
A
P
G
G
G
G
K
Rhesus Macaque
Macaca mulatta
XP_001085111
261
29741
S198
A
P
V
S
I
Q
R
S
A
P
G
G
G
G
K
Dog
Lupus familis
XP_851714
257
29048
R194
A
A
P
V
S
I
P
R
S
A
P
G
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61792
263
29976
Q198
P
A
A
P
V
S
I
Q
R
S
A
P
G
G
G
Rat
Rattus norvegicus
Q99MZ8
263
29952
Q198
P
A
A
P
V
S
I
Q
R
S
A
P
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516545
118
13511
H56
K
K
P
Y
C
N
A
H
Y
P
K
Q
S
F
T
Chicken
Gallus gallus
Q01406
563
63311
T410
Q
A
K
A
K
K
Q
T
P
P
P
S
P
T
T
Frog
Xenopus laevis
Q6GM14
376
42749
T312
Q
E
D
P
V
Y
E
T
G
V
A
E
D
S
G
Zebra Danio
Brachydanio rerio
NP_997801
234
26681
P172
V
R
P
A
A
A
A
P
P
P
S
S
G
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I7C3
657
74228
L198
Y
Q
Q
H
Q
Q
Q
L
Q
Q
Q
Q
H
Q
H
Honey Bee
Apis mellifera
XP_001121584
320
35562
A198
A
R
P
S
P
Y
S
A
R
Q
A
A
T
T
V
Nematode Worm
Caenorhab. elegans
P34416
335
37006
N200
I
A
D
Y
D
P
M
N
G
Q
W
G
T
A
A
Sea Urchin
Strong. purpuratus
XP_797085
249
27176
P187
Q
L
S
A
P
P
P
P
A
A
S
S
G
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.7
98.4
94.6
N.A.
95.4
96.1
N.A.
41.7
21.3
21.8
68.5
N.A.
23.1
42.1
37.3
50.1
Protein Similarity:
100
66.7
99.2
95.7
N.A.
97.3
97.3
N.A.
43.6
30.5
38
75.4
N.A.
30.4
53.4
51
60.5
P-Site Identity:
100
100
100
26.6
N.A.
13.3
13.3
N.A.
6.6
6.6
0
13.3
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
20
20
N.A.
6.6
33.3
13.3
26.6
N.A.
13.3
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
36
15
22
8
8
15
8
29
15
29
8
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
8
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
0
22
36
58
43
29
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
8
% H
% Ile:
8
0
0
0
22
8
15
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
0
8
8
0
0
0
0
8
0
0
8
22
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
15
22
29
22
15
15
15
15
15
43
15
15
8
8
0
% P
% Gln:
22
8
8
0
8
29
15
15
8
22
8
15
0
8
8
% Q
% Arg:
0
15
0
0
0
0
22
8
22
0
0
0
0
0
8
% R
% Ser:
0
0
8
29
8
15
8
22
8
15
15
22
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
0
0
15
15
15
% T
% Val:
8
0
22
8
22
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
15
0
15
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _