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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM3
All Species:
19.7
Human Site:
T718
Identified Species:
36.11
UniProt:
Q14832
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14832
NP_000831.2
879
98879
T718
A
P
G
T
R
R
Y
T
L
A
E
K
R
E
T
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
M690
A
F
I
T
V
L
K
M
V
I
V
V
I
G
M
Rhesus Macaque
Macaca mulatta
XP_001107588
879
98905
T718
A
P
G
T
R
R
Y
T
L
A
E
K
R
E
T
Dog
Lupus familis
XP_541867
872
95696
T709
A
P
G
T
G
K
E
T
A
P
E
R
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYS2
879
99096
T718
T
P
G
T
R
R
Y
T
L
P
E
K
R
E
T
Rat
Rattus norvegicus
P31422
879
98942
T718
T
P
G
T
R
R
Y
T
L
P
E
K
R
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515487
775
87278
N627
E
T
V
I
L
K
C
N
V
K
D
S
S
M
L
Chicken
Gallus gallus
XP_416842
879
98936
T718
A
P
G
T
R
R
Y
T
L
P
E
K
R
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
K703
L
Y
K
P
F
K
D
K
E
V
Q
T
E
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
F766
V
E
P
P
G
T
R
F
Y
Y
P
D
R
R
E
Honey Bee
Apis mellifera
NP_001011624
933
103448
F745
I
E
P
P
G
T
R
F
F
Y
P
D
R
K
Q
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
H819
V
V
P
P
G
W
R
H
H
Y
P
T
R
D
Q
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
R1291
D
P
P
S
T
V
T
R
F
A
E
D
R
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
99.5
68.7
N.A.
96.6
96.5
N.A.
79.1
91
N.A.
26.5
N.A.
46
48.2
39.4
33.3
Protein Similarity:
100
45.3
99.6
82.3
N.A.
98.7
98.5
N.A.
83.8
95.4
N.A.
46
N.A.
61.6
64.7
57.1
44.9
P-Site Identity:
100
13.3
100
53.3
N.A.
86.6
86.6
N.A.
0
93.3
N.A.
0
N.A.
6.6
6.6
6.6
26.6
P-Site Similarity:
100
20
100
66.6
N.A.
86.6
86.6
N.A.
20
93.3
N.A.
13.3
N.A.
6.6
13.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
0
0
0
0
8
24
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
8
24
0
8
0
% D
% Glu:
8
16
0
0
0
0
8
0
8
0
54
0
8
47
16
% E
% Phe:
0
8
0
0
8
0
0
16
16
0
0
0
0
0
0
% F
% Gly:
0
0
47
0
31
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
0
0
0
0
8
0
0
8
0
8
% I
% Lys:
0
0
8
0
0
24
8
8
0
8
0
39
0
8
0
% K
% Leu:
8
0
0
0
8
8
0
0
39
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
54
31
31
0
0
0
0
0
31
24
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
16
% Q
% Arg:
0
0
0
0
39
39
24
8
0
0
0
8
77
8
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
8
8
16
0
% S
% Thr:
16
8
0
54
8
16
8
47
0
0
0
16
0
0
39
% T
% Val:
16
8
8
0
8
8
0
0
16
8
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
39
0
8
24
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _