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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM3
All Species:
42.42
Human Site:
S218
Identified Species:
77.78
UniProt:
Q14832
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14832
NP_000831.2
879
98879
S218
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
S211
N
W
I
I
V
L
V
S
S
D
T
Y
G
R
D
Rhesus Macaque
Macaca mulatta
XP_001107588
879
98905
S218
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Dog
Lupus familis
XP_541867
872
95696
S212
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYS2
879
99096
S218
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Rat
Rattus norvegicus
P31422
879
98942
S218
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515487
775
87278
T163
I
R
E
L
L
Q
K
T
N
A
R
V
V
V
L
Chicken
Gallus gallus
XP_416842
879
98936
S218
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
T217
S
W
V
G
I
I
I
T
D
G
D
Y
G
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
S225
S
Y
V
S
T
I
H
S
E
G
S
Y
G
E
Y
Honey Bee
Apis mellifera
NP_001011624
933
103448
S236
S
Y
V
S
T
V
Y
S
E
G
S
Y
G
E
Y
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
S269
S
Y
V
S
L
V
Y
S
A
D
E
Y
G
E
L
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
S786
T
Y
V
S
T
V
W
S
S
G
E
Y
G
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.9
99.5
68.7
N.A.
96.6
96.5
N.A.
79.1
91
N.A.
26.5
N.A.
46
48.2
39.4
33.3
Protein Similarity:
100
45.3
99.6
82.3
N.A.
98.7
98.5
N.A.
83.8
95.4
N.A.
46
N.A.
61.6
64.7
57.1
44.9
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
0
100
N.A.
33.3
N.A.
66.6
73.3
53.3
73.3
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
73.3
N.A.
80
80
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
47
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
16
54
0
0
0
8
% D
% Glu:
0
0
8
0
0
0
0
0
62
0
16
0
0
77
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
77
0
0
93
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
8
16
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
16
8
0
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
0
0
16
0
% R
% Ser:
31
0
0
77
0
0
0
85
16
0
16
0
0
0
16
% S
% Thr:
54
0
0
0
70
0
0
16
0
0
8
0
0
0
47
% T
% Val:
0
0
85
0
8
70
8
0
0
0
0
8
8
8
0
% V
% Trp:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
77
0
0
0
0
16
0
0
0
0
93
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _