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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MESDC2
All Species:
10.61
Human Site:
Y166
Identified Species:
17.95
UniProt:
Q14696
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14696
NP_055969.1
234
26077
Y166
F
M
L
R
D
G
S
Y
A
W
E
I
K
D
F
Chimpanzee
Pan troglodytes
XP_001161202
85
9478
V26
W
E
I
K
D
F
L
V
G
Q
D
R
C
A
D
Rhesus Macaque
Macaca mulatta
XP_001109767
149
16578
P90
E
H
K
R
P
S
A
P
V
D
F
S
K
I
D
Dog
Lupus familis
XP_545883
190
21252
D131
K
D
F
L
V
S
Q
D
R
C
A
D
V
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERE7
224
25188
Y157
F
M
L
R
D
G
S
Y
A
W
E
I
K
D
F
Rat
Rattus norvegicus
Q5U2R7
224
25197
Y157
F
M
L
R
D
G
S
Y
A
W
E
I
K
D
F
Wallaby
Macropus eugenll
Q9XT48
201
21518
V142
S
S
K
Y
Q
V
H
V
P
L
L
S
A
Q
K
Platypus
Ornith. anatinus
XP_001514817
161
18036
F102
Y
A
W
E
I
K
D
F
L
V
N
Q
D
R
C
Chicken
Gallus gallus
Q5ZKK4
220
24673
W152
L
R
D
G
G
Y
A
W
E
I
K
D
F
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L243
206
23288
A147
M
L
R
D
G
S
Y
A
W
E
I
K
D
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T9B6
180
20983
W121
K
L
W
Q
T
S
L
W
N
N
H
I
Q
A
E
Honey Bee
Apis mellifera
XP_001122588
178
21016
T119
M
I
M
R
I
W
Q
T
S
L
Q
N
N
H
I
Nematode Worm
Caenorhab. elegans
NP_495003
186
21786
V127
S
Q
L
Y
N
N
H
V
D
L
Q
V
F
V
I
Sea Urchin
Strong. purpuratus
XP_001188878
182
21140
Q123
M
K
N
F
L
L
E
Q
D
R
C
Q
E
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.9
61.1
67.5
N.A.
83.7
81.6
21.3
59.4
74.3
N.A.
64
N.A.
38.8
30.3
34.6
38.4
Protein Similarity:
100
36.3
62.8
73.5
N.A.
90.5
88.8
35.4
64
80.3
N.A.
73.9
N.A.
56.4
49.5
52.1
53.8
P-Site Identity:
100
6.6
13.3
0
N.A.
100
100
0
0
0
N.A.
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
33.3
20
0
N.A.
100
100
0
13.3
20
N.A.
6.6
N.A.
33.3
33.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
15
8
22
0
8
0
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
8
% C
% Asp:
0
8
8
8
29
0
8
8
15
8
8
15
15
22
15
% D
% Glu:
8
8
0
8
0
0
8
0
8
8
22
0
8
0
8
% E
% Phe:
22
0
8
8
0
8
0
8
0
0
8
0
15
8
22
% F
% Gly:
0
0
0
8
15
22
0
0
8
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
15
0
0
0
8
0
0
8
0
% H
% Ile:
0
8
8
0
15
0
0
0
0
8
8
29
0
8
22
% I
% Lys:
15
8
15
8
0
8
0
0
0
0
8
8
29
0
8
% K
% Leu:
8
15
29
8
8
8
15
0
8
22
8
0
0
8
15
% L
% Met:
22
22
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
8
0
0
8
8
8
8
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
8
0
15
8
0
8
15
15
8
8
0
% Q
% Arg:
0
8
8
36
0
0
0
0
8
8
0
8
0
8
0
% R
% Ser:
15
8
0
0
0
29
22
0
8
0
0
15
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
8
8
0
22
8
8
0
8
8
15
0
% V
% Trp:
8
0
15
0
0
8
0
15
8
22
0
0
0
0
0
% W
% Tyr:
8
0
0
15
0
8
8
22
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _