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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1A
All Species:
18.18
Human Site:
T443
Identified Species:
26.67
UniProt:
Q14683
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.47
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14683
NP_006297.2
1233
143233
T443
E
K
L
E
E
Y
I
T
T
S
K
Q
S
L
E
Chimpanzee
Pan troglodytes
XP_515195
1235
143766
K443
E
K
L
E
E
Y
T
K
T
C
M
D
C
L
K
Rhesus Macaque
Macaca mulatta
XP_001091228
1196
139006
T443
E
K
L
E
E
Y
I
T
T
S
K
Q
S
L
E
Dog
Lupus familis
XP_538049
1295
149661
T505
E
K
L
E
E
Y
I
T
T
S
K
Q
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CU62
1233
143197
T443
E
K
L
E
E
Y
I
T
T
S
K
Q
S
L
E
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
T443
E
K
L
E
E
Y
I
T
T
S
K
Q
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
K414
E
K
L
E
E
Y
A
K
I
C
I
T
C
L
K
Chicken
Gallus gallus
Q90988
1189
134923
K445
K
K
M
D
G
S
Y
K
E
D
Q
E
A
F
E
Frog
Xenopus laevis
O93308
1232
142609
A443
E
K
L
E
E
Y
I
A
T
S
K
Q
S
L
E
Zebra Danio
Brachydanio rerio
NP_001155103
1232
143125
A443
E
K
L
E
D
Y
I
A
T
S
R
Q
S
L
D
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
K447
E
K
L
E
E
Y
A
K
N
C
R
Y
T
L
D
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
K466
D
K
L
M
D
H
I
K
S
S
Q
A
A
L
E
Honey Bee
Apis mellifera
XP_395059
1230
141414
R444
E
K
L
E
E
H
I
R
T
S
E
A
A
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
R443
E
K
L
N
D
Y
I
R
A
S
E
A
N
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
I498
K
K
K
K
Q
E
A
I
E
A
R
K
V
E
E
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
N451
E
K
L
D
T
Q
L
N
D
L
R
V
S
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
97
95.1
N.A.
99.4
99.5
N.A.
48.9
25.1
93.8
89.1
46.9
49
54.7
N.A.
62.7
Protein Similarity:
100
74.6
97
95.1
N.A.
99.8
99.6
N.A.
68.1
46.7
96.5
95.4
70.2
70.3
73.6
N.A.
79.9
P-Site Identity:
100
53.3
100
100
N.A.
100
100
N.A.
46.6
13.3
93.3
73.3
46.6
40
66.6
N.A.
40
P-Site Similarity:
100
60
100
100
N.A.
100
100
N.A.
53.3
53.3
93.3
93.3
66.6
80
86.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
13
7
7
0
19
19
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
19
0
0
13
0
0
% C
% Asp:
7
0
0
13
19
0
0
0
7
7
0
7
0
0
13
% D
% Glu:
82
0
0
69
63
7
0
0
13
0
13
7
0
7
63
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
63
7
7
0
7
0
0
7
0
% I
% Lys:
13
100
7
7
0
0
0
32
0
0
38
7
0
0
13
% K
% Leu:
0
0
88
0
0
0
7
0
0
7
0
0
0
82
0
% L
% Met:
0
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
7
7
0
0
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
0
0
0
0
13
44
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
0
25
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
7
63
0
0
50
0
0
% S
% Thr:
0
0
0
0
7
0
7
32
57
0
0
7
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
69
7
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _