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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5A
All Species:
21.52
Human Site:
Y227
Identified Species:
43.03
UniProt:
Q14642
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14642
NP_005530.3
412
47820
Y227
Q
R
F
E
K
V
S
Y
F
V
F
G
D
F
N
Chimpanzee
Pan troglodytes
XP_001155993
414
48224
Y227
Q
R
F
E
K
V
S
Y
F
V
F
G
D
F
N
Rhesus Macaque
Macaca mulatta
XP_001113817
361
41727
E210
V
R
A
A
D
T
N
E
V
V
K
L
I
F
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_898967
422
48794
Y227
Q
R
F
E
K
V
S
Y
F
V
F
G
D
F
N
Rat
Rattus norvegicus
NP_001102393
412
47604
Y227
Q
R
F
E
K
V
S
Y
F
V
F
G
D
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421831
502
57686
Y317
Q
R
F
E
K
V
S
Y
F
V
F
G
D
F
N
Frog
Xenopus laevis
NP_001087708
412
47382
F227
H
R
F
E
K
V
P
F
F
V
F
G
D
F
N
Zebra Danio
Brachydanio rerio
NP_001032658
396
45953
S222
N
T
Y
S
P
L
P
S
F
L
F
G
D
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138109
786
88564
G229
F
H
L
D
E
Q
N
G
T
V
P
F
F
L
F
Honey Bee
Apis mellifera
NP_001011585
388
45250
S219
R
F
H
N
D
K
Y
S
N
V
P
Y
F
L
F
Nematode Worm
Caenorhab. elegans
Q17848
409
47583
L219
E
N
G
C
T
P
L
L
F
V
F
G
D
L
N
Sea Urchin
Strong. purpuratus
XP_782162
345
40063
P194
A
L
V
L
Q
A
K
P
T
Y
T
K
K
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
66.5
N.A.
N.A.
92.4
97
N.A.
N.A.
74.3
82.7
52.6
N.A.
24.5
49.2
29.3
39
Protein Similarity:
100
96.8
73.7
N.A.
N.A.
94.5
98.7
N.A.
N.A.
78.8
91.2
69.9
N.A.
35.3
66
49.7
55.3
P-Site Identity:
100
100
20
N.A.
N.A.
100
100
N.A.
N.A.
100
80
40
N.A.
6.6
6.6
40
0
P-Site Similarity:
100
100
26.6
N.A.
N.A.
100
100
N.A.
N.A.
100
86.6
60
N.A.
26.6
13.3
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
17
0
0
0
0
0
0
0
67
9
0
% D
% Glu:
9
0
0
50
9
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
9
9
50
0
0
0
0
9
67
0
67
9
17
67
17
% F
% Gly:
0
0
9
0
0
0
0
9
0
0
0
67
0
0
9
% G
% His:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
50
9
9
0
0
0
9
9
9
0
0
% K
% Leu:
0
9
9
9
0
9
9
9
0
9
0
9
0
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
9
0
0
17
0
9
0
0
0
0
0
67
% N
% Pro:
0
0
0
0
9
9
17
9
0
0
17
0
0
0
0
% P
% Gln:
42
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
59
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
9
0
0
42
17
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
9
9
0
0
17
0
9
0
0
0
0
% T
% Val:
9
0
9
0
0
50
0
0
9
84
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
42
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _