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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5A
All Species:
22.42
Human Site:
S66
Identified Species:
44.85
UniProt:
Q14642
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14642
NP_005530.3
412
47820
S66
K
N
Y
E
A
S
M
S
H
V
D
K
F
V
K
Chimpanzee
Pan troglodytes
XP_001155993
414
48224
S66
K
N
Y
E
A
S
M
S
H
V
D
K
F
V
K
Rhesus Macaque
Macaca mulatta
XP_001113817
361
41727
L55
A
L
G
S
F
Y
F
L
H
E
S
L
K
N
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_898967
422
48794
S66
K
N
Y
E
A
S
M
S
H
V
D
K
F
V
K
Rat
Rattus norvegicus
NP_001102393
412
47604
S66
K
N
Y
E
A
S
M
S
H
V
D
K
F
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421831
502
57686
S156
K
N
Y
E
A
S
M
S
H
V
D
K
F
V
K
Frog
Xenopus laevis
NP_001087708
412
47382
S66
K
N
Y
E
A
S
M
S
H
V
D
K
L
V
K
Zebra Danio
Brachydanio rerio
NP_001032658
396
45953
G61
K
D
Y
M
V
N
M
G
H
A
E
N
F
F
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138109
786
88564
E67
K
T
Y
E
K
S
M
E
Y
V
Q
E
F
I
R
Honey Bee
Apis mellifera
NP_001011585
388
45250
R62
K
N
Y
E
H
S
T
R
Q
V
E
D
F
V
R
Nematode Worm
Caenorhab. elegans
Q17848
409
47583
Q58
K
K
F
T
E
C
S
Q
Q
V
P
I
I
I
N
Sea Urchin
Strong. purpuratus
XP_782162
345
40063
K39
D
K
L
Y
E
T
I
K
R
L
E
P
H
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
66.5
N.A.
N.A.
92.4
97
N.A.
N.A.
74.3
82.7
52.6
N.A.
24.5
49.2
29.3
39
Protein Similarity:
100
96.8
73.7
N.A.
N.A.
94.5
98.7
N.A.
N.A.
78.8
91.2
69.9
N.A.
35.3
66
49.7
55.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
N.A.
100
93.3
33.3
N.A.
46.6
53.3
13.3
0
P-Site Similarity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
N.A.
100
93.3
53.3
N.A.
73.3
66.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
50
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
0
0
0
50
9
0
0
0
% D
% Glu:
0
0
0
67
17
0
0
9
0
9
25
9
0
0
0
% E
% Phe:
0
0
9
0
9
0
9
0
0
0
0
0
67
17
0
% F
% Gly:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
67
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
9
9
17
17
% I
% Lys:
84
17
0
0
9
0
0
9
0
0
0
50
9
0
50
% K
% Leu:
0
9
9
0
0
0
0
9
0
9
0
9
9
0
0
% L
% Met:
0
0
0
9
0
0
67
0
0
0
0
0
0
0
0
% M
% Asn:
0
59
0
0
0
9
0
0
0
0
0
9
0
9
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
17
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
17
% R
% Ser:
0
0
0
9
0
67
9
50
0
0
9
0
0
0
0
% S
% Thr:
0
9
0
9
0
9
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
75
0
0
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
75
9
0
9
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _