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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5A
All Species:
25.76
Human Site:
S241
Identified Species:
51.52
UniProt:
Q14642
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14642
NP_005530.3
412
47820
S241
N
F
R
L
D
S
K
S
V
V
E
T
L
C
T
Chimpanzee
Pan troglodytes
XP_001155993
414
48224
S241
N
F
R
L
D
S
K
S
V
V
E
T
L
C
T
Rhesus Macaque
Macaca mulatta
XP_001113817
361
41727
K224
R
E
S
D
N
D
R
K
V
M
L
Q
L
E
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_898967
422
48794
S241
N
F
R
L
D
S
K
S
V
V
E
T
L
C
T
Rat
Rattus norvegicus
NP_001102393
412
47604
S241
N
F
R
L
D
S
K
S
V
V
E
T
L
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421831
502
57686
A331
N
F
R
L
D
A
K
A
V
V
E
T
L
C
A
Frog
Xenopus laevis
NP_001087708
412
47382
S241
N
F
R
L
D
L
K
S
V
V
E
T
L
C
A
Zebra Danio
Brachydanio rerio
NP_001032658
396
45953
S236
N
F
R
L
D
T
L
S
L
V
Q
N
L
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138109
786
88564
C243
F
G
D
F
N
F
R
C
D
T
E
G
V
V
K
Honey Bee
Apis mellifera
NP_001011585
388
45250
T233
F
G
D
F
N
F
R
T
D
T
A
G
V
I
K
Nematode Worm
Caenorhab. elegans
Q17848
409
47583
S233
N
F
R
L
D
S
R
S
F
L
N
R
L
T
E
Sea Urchin
Strong. purpuratus
XP_782162
345
40063
Y208
G
A
I
T
R
I
E
Y
S
D
E
N
N
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
66.5
N.A.
N.A.
92.4
97
N.A.
N.A.
74.3
82.7
52.6
N.A.
24.5
49.2
29.3
39
Protein Similarity:
100
96.8
73.7
N.A.
N.A.
94.5
98.7
N.A.
N.A.
78.8
91.2
69.9
N.A.
35.3
66
49.7
55.3
P-Site Identity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
N.A.
80
86.6
53.3
N.A.
6.6
0
53.3
6.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
N.A.
93.3
86.6
73.3
N.A.
26.6
26.6
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
9
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
50
0
% C
% Asp:
0
0
17
9
67
9
0
0
17
9
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
9
0
0
0
67
0
0
9
9
% E
% Phe:
17
67
0
17
0
17
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
17
0
0
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
50
9
0
0
0
0
0
0
25
% K
% Leu:
0
0
0
67
0
9
9
0
9
9
9
0
75
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
67
0
0
0
25
0
0
0
0
0
9
17
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% Q
% Arg:
9
0
67
0
9
0
34
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
9
0
0
42
0
59
9
0
0
0
0
17
0
% S
% Thr:
0
0
0
9
0
9
0
9
0
17
0
50
0
9
34
% T
% Val:
0
0
0
0
0
0
0
0
59
59
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _