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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5A
All Species:
25.45
Human Site:
S137
Identified Species:
50.91
UniProt:
Q14642
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14642
NP_005530.3
412
47820
S137
V
A
G
K
E
I
Y
S
D
T
L
E
S
T
P
Chimpanzee
Pan troglodytes
XP_001155993
414
48224
S137
V
A
G
K
E
I
Y
S
D
T
L
E
S
T
P
Rhesus Macaque
Macaca mulatta
XP_001113817
361
41727
I126
A
D
C
A
F
N
L
I
N
I
G
T
F
N
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_898967
422
48794
S137
V
T
G
K
E
I
Y
S
D
T
L
E
S
T
P
Rat
Rattus norvegicus
NP_001102393
412
47604
S137
V
T
G
K
E
I
Y
S
D
T
L
E
S
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421831
502
57686
S227
V
T
G
K
E
I
Y
S
D
T
L
E
S
T
P
Frog
Xenopus laevis
NP_001087708
412
47382
S137
V
T
G
K
E
I
Y
S
D
T
L
E
S
T
P
Zebra Danio
Brachydanio rerio
NP_001032658
396
45953
V132
V
S
G
H
N
K
Y
V
G
S
L
D
G
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138109
786
88564
K138
S
L
Q
D
V
K
D
K
H
I
Y
S
G
N
I
Honey Bee
Apis mellifera
NP_001011585
388
45250
S133
V
N
G
K
E
V
H
S
G
N
I
E
A
V
T
Nematode Worm
Caenorhab. elegans
Q17848
409
47583
H129
S
P
K
E
V
V
T
H
G
L
E
N
Y
P
Y
Sea Urchin
Strong. purpuratus
XP_782162
345
40063
T110
S
R
K
G
F
M
R
T
R
W
S
I
N
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
66.5
N.A.
N.A.
92.4
97
N.A.
N.A.
74.3
82.7
52.6
N.A.
24.5
49.2
29.3
39
Protein Similarity:
100
96.8
73.7
N.A.
N.A.
94.5
98.7
N.A.
N.A.
78.8
91.2
69.9
N.A.
35.3
66
49.7
55.3
P-Site Identity:
100
100
0
N.A.
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
26.6
N.A.
0
40
0
0
P-Site Similarity:
100
100
6.6
N.A.
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
46.6
N.A.
0
66.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
9
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
9
0
50
0
0
9
0
0
0
% D
% Glu:
0
0
0
9
59
0
0
0
0
0
9
59
0
0
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
0
67
9
0
0
0
0
25
0
9
0
17
9
0
% G
% His:
0
0
0
9
0
0
9
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
9
0
17
9
9
0
0
9
% I
% Lys:
0
0
17
59
0
17
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
9
0
0
9
59
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
9
0
0
9
9
0
9
9
17
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
50
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
9
0
9
0
0
0
0
0
9
% R
% Ser:
25
9
0
0
0
0
0
59
0
9
9
9
50
0
0
% S
% Thr:
0
34
0
0
0
0
9
9
0
50
0
9
0
50
17
% T
% Val:
67
0
0
0
17
17
0
9
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
59
0
0
0
9
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _