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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90AA2
All Species:
35.45
Human Site:
T99
Identified Species:
60
UniProt:
Q14568
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14568
NP_005339
343
39365
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Chimpanzee
Pan troglodytes
A5A6K9
733
84754
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Rhesus Macaque
Macaca mulatta
XP_001098426
696
80269
D364
V
R
R
V
F
I
M
D
S
C
D
E
L
I
P
Dog
Lupus familis
XP_848783
483
56243
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Cat
Felis silvestris
Mouse
Mus musculus
P07901
733
84769
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Rat
Rattus norvegicus
P82995
733
84796
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512830
733
84847
T99
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Chicken
Gallus gallus
P11501
728
84041
T98
V
D
T
G
I
G
M
T
K
A
D
L
V
N
N
Frog
Xenopus laevis
NP_001085598
729
84174
T100
I
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Zebra Danio
Brachydanio rerio
Q90474
725
83300
S166
W
E
S
A
A
G
G
S
F
T
V
K
P
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
F158
E
S
S
A
G
G
S
F
T
V
R
A
D
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
S128
Q
F
G
V
G
F
Y
S
A
F
L
V
A
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55737
699
80046
D343
V
R
R
V
F
I
M
D
N
C
E
D
I
I
P
Baker's Yeast
Sacchar. cerevisiae
P15108
705
80881
T157
S
N
A
G
G
S
F
T
V
T
L
D
E
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45
39.6
67.6
N.A.
44.8
45
N.A.
42.9
40.5
39.3
36.9
N.A.
36.8
N.A.
34.1
N.A.
Protein Similarity:
100
45.5
44.4
68.9
N.A.
45.5
45.5
N.A.
44.7
43.1
42.7
43
N.A.
41.4
N.A.
41.3
N.A.
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
100
93.3
93.3
6.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
100
100
33.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.4
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
8
0
0
0
8
58
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
0
58
0
0
0
0
0
15
0
0
65
15
8
15
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
8
8
8
0
0
% E
% Phe:
0
8
0
0
15
8
8
8
8
8
0
0
0
0
8
% F
% Gly:
0
0
8
65
22
72
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
58
15
0
0
0
0
0
0
58
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
58
0
0
8
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
15
58
8
0
0
% L
% Met:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
0
0
65
65
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
15
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
15
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
8
15
0
0
8
8
15
8
0
0
0
0
0
8
% S
% Thr:
0
0
58
0
0
0
0
65
8
15
0
0
0
0
0
% T
% Val:
65
0
0
22
0
0
0
0
8
8
8
8
8
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _