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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX8 All Species: 33.64
Human Site: T963 Identified Species: 61.67
UniProt: Q14562 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14562 NP_004932.1 1220 139315 T963 T A M E Q L Y T L G A L D D E
Chimpanzee Pan troglodytes Q7YR39 1044 119631 E810 G A L N H L G E L T T S G R K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537627 1216 138553 T959 T A M E Q L Y T L G A L D D E
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 T987 T A M E Q L Y T L G A L D D E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418105 1076 123154 E842 R M A E F P L E P M L C K M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663993 1210 138002 T953 T A M E Q L Y T L G A L D D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610928 1242 141917 S984 M A L E Q L H S L S A L D D E
Honey Bee Apis mellifera XP_623289 1192 136394 S934 M A L E S L H S L S A L D N E
Nematode Worm Caenorhab. elegans Q09530 1200 135741 T938 T A L N T L H T L S A L D G D
Sea Urchin Strong. purpuratus O17438 455 51461 V221 V Y N P R I R V E S L L V S P
Poplar Tree Populus trichocarpa XP_002318357 1207 137837 S952 S A L E Q L Y S L G A L D E E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 S913 S A M E Q L Y S L G A L D E E
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 H881 N A L T E L Y H L Q S L D D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40 N.A. 98.5 N.A. 96.8 N.A. N.A. N.A. 84 N.A. 91.1 N.A. 69.4 71.8 61.3 21.9
Protein Similarity: 100 59 N.A. 99.1 N.A. 97.3 N.A. N.A. N.A. 86.8 N.A. 94.5 N.A. 82 83.9 75.4 28.8
P-Site Identity: 100 20 N.A. 100 N.A. 100 N.A. N.A. N.A. 6.6 N.A. 100 N.A. 66.6 53.3 53.3 6.6
P-Site Similarity: 100 33.3 N.A. 100 N.A. 100 N.A. N.A. N.A. 6.6 N.A. 100 N.A. 86.6 80 73.3 20
Percent
Protein Identity: 59.1 N.A. N.A. 59.3 44.2 N.A.
Protein Similarity: 75 N.A. N.A. 75.4 62.8 N.A.
P-Site Identity: 73.3 N.A. N.A. 80 53.3 N.A.
P-Site Similarity: 100 N.A. N.A. 100 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 85 8 0 0 0 0 0 0 0 70 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 77 47 8 % D
% Glu: 0 0 0 70 8 0 0 16 8 0 0 0 0 16 70 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 0 47 0 0 8 8 0 % G
% His: 0 0 0 0 8 0 24 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % K
% Leu: 0 0 47 0 0 85 8 0 85 0 16 85 0 0 8 % L
% Met: 16 8 39 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 8 0 8 16 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 54 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 8 0 0 0 8 0 8 0 0 0 0 0 0 8 0 % R
% Ser: 16 0 0 0 8 0 0 31 0 31 8 8 0 8 0 % S
% Thr: 39 0 0 8 8 0 0 39 0 8 8 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 54 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _