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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPSAP1 All Species: 35.76
Human Site: Y278 Identified Species: 71.52
UniProt: Q14558 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14558 NP_002757.2 356 39394 Y278 I L K E R G A Y K I Y V M A T
Chimpanzee Pan troglodytes XP_001151480 357 39370 Y279 I L K E R G A Y K I Y V M A T
Rhesus Macaque Macaca mulatta XP_001104513 385 42500 Y307 I L K E R G A Y K I Y V M A T
Dog Lupus familis XP_849109 385 42468 Y307 I L K E R G A Y K I Y V M A T
Cat Felis silvestris
Mouse Mus musculus Q9D0M1 356 39413 Y278 I L K E R G A Y K I Y V M A T
Rat Rattus norvegicus Q63468 356 39417 Y278 T L K E R G A Y K I Y V M A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL26 369 40785 Y291 T L K E R G A Y K I F V M A T
Frog Xenopus laevis Q7ZXC9 318 34683 A241 D K L L S A G A T K V Y A I L
Zebra Danio Brachydanio rerio NP_001002199 353 39121 Y275 I L K E R G A Y K I Y I M A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733387 367 40516 C289 M L K E N G A C K I Y V L A T
Honey Bee Apis mellifera XP_624652 354 39047 Y276 V L K E R G A Y K I Y V L A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38689 320 35105 A243 E I L L E N R A K S V I A I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 91.9 92.2 N.A. 99.1 98.5 N.A. N.A. 76.4 43.8 89 N.A. 62.4 68.2 N.A. N.A.
Protein Similarity: 100 96.6 91.9 92.4 N.A. 99.7 99.1 N.A. N.A. 87.5 60.9 95.5 N.A. 79 83.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 86.6 0 93.3 N.A. 73.3 86.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 93.3 0 100 N.A. 86.6 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 41.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 57.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 84 17 0 0 0 0 17 84 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 84 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 84 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 50 9 0 0 0 0 0 0 0 84 0 17 0 17 0 % I
% Lys: 0 9 84 0 0 0 0 0 92 9 0 0 0 0 0 % K
% Leu: 0 84 17 17 0 0 0 0 0 0 0 0 17 0 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 75 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % S
% Thr: 17 0 0 0 0 0 0 0 9 0 0 0 0 0 84 % T
% Val: 9 0 0 0 0 0 0 0 0 0 17 75 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 75 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _