KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPSAP1
All Species:
25.45
Human Site:
T223
Identified Species:
50.91
UniProt:
Q14558
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14558
NP_002757.2
356
39394
T223
P
P
M
V
K
N
A
T
V
H
P
G
L
E
L
Chimpanzee
Pan troglodytes
XP_001151480
357
39370
T224
P
P
M
V
K
N
A
T
V
H
P
G
L
E
L
Rhesus Macaque
Macaca mulatta
XP_001104513
385
42500
T252
P
P
M
V
K
N
A
T
V
H
P
G
L
E
L
Dog
Lupus familis
XP_849109
385
42468
T252
P
P
M
V
K
N
A
T
V
H
P
G
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M1
356
39413
T223
P
P
M
V
K
N
A
T
V
H
P
G
L
E
L
Rat
Rattus norvegicus
Q63468
356
39417
T223
P
P
M
V
K
N
A
T
V
H
P
G
L
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL26
369
40785
A235
P
P
T
A
K
N
V
A
A
I
H
R
S
L
E
Frog
Xenopus laevis
Q7ZXC9
318
34683
K197
A
L
I
H
K
E
R
K
K
A
N
E
V
D
R
Zebra Danio
Brachydanio rerio
NP_001002199
353
39121
I220
P
P
C
V
R
N
T
I
G
H
P
G
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733387
367
40516
P222
P
P
T
R
N
S
T
P
Q
H
A
P
T
S
S
Honey Bee
Apis mellifera
XP_624652
354
39047
T221
P
P
A
L
A
S
R
T
M
E
V
G
V
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38689
320
35105
A199
A
L
I
H
K
E
R
A
R
A
N
E
V
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
91.9
92.2
N.A.
99.1
98.5
N.A.
N.A.
76.4
43.8
89
N.A.
62.4
68.2
N.A.
N.A.
Protein Similarity:
100
96.6
91.9
92.4
N.A.
99.7
99.1
N.A.
N.A.
87.5
60.9
95.5
N.A.
79
83.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
6.6
66.6
N.A.
20
26.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
26.6
73.3
N.A.
26.6
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
41.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
9
9
0
50
17
9
17
9
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
17
0
0
0
9
0
17
0
59
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
67
0
9
0
% G
% His:
0
0
0
17
0
0
0
0
0
67
9
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
9
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
75
0
0
9
9
0
0
0
0
0
0
% K
% Leu:
0
17
0
9
0
0
0
0
0
0
0
0
59
9
59
% L
% Met:
0
0
50
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
67
0
0
0
0
17
0
0
0
0
% N
% Pro:
84
84
0
0
0
0
0
9
0
0
59
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
25
0
9
0
0
9
0
0
17
% R
% Ser:
0
0
0
0
0
17
0
0
0
0
0
0
9
17
9
% S
% Thr:
0
0
17
0
0
0
17
59
0
0
0
0
9
0
0
% T
% Val:
0
0
0
59
0
0
9
0
50
0
9
0
25
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _