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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPARCL1
All Species:
10.61
Human Site:
S127
Identified Species:
21.21
UniProt:
Q14515
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14515
NP_001121782.1
664
75208
S127
L
D
I
K
E
D
M
S
E
P
Q
E
K
K
L
Chimpanzee
Pan troglodytes
NP_001092036
664
75006
S127
L
D
I
K
E
D
M
S
E
P
Q
E
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001097634
661
74967
S127
L
D
I
K
E
D
M
S
E
P
Q
E
K
K
P
Dog
Lupus familis
XP_850045
667
76180
G136
L
D
L
K
E
D
M
G
E
P
Q
N
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P70663
650
72296
P127
E
P
Q
Q
K
S
L
P
E
N
G
D
F
P
A
Rat
Rattus norvegicus
P24054
634
70615
D127
K
R
L
P
E
N
A
D
F
P
A
T
V
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513120
452
50460
Chicken
Gallus gallus
P36377
298
34042
Frog
Xenopus laevis
P36378
300
34577
Zebra Danio
Brachydanio rerio
NP_001124077
606
68981
S123
D
E
D
D
H
S
E
S
L
E
K
D
E
V
M
Tiger Blowfish
Takifugu rubipres
NP_001027724
652
72948
E127
E
E
E
E
A
E
V
E
E
G
K
E
Q
S
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34714
264
30154
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
93.2
76.4
N.A.
64.6
64
N.A.
41.1
28.9
26.9
33.7
32.6
N.A.
N.A.
21.3
N.A.
Protein Similarity:
100
98.4
94.7
86.3
N.A.
74.2
75.1
N.A.
53
35.3
34.9
50.9
47.7
N.A.
N.A.
28.1
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
6.6
13.3
N.A.
0
0
0
6.6
13.3
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
33.3
26.6
N.A.
0
0
0
40
60
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
34
9
9
0
34
0
9
0
0
0
17
0
0
0
% D
% Glu:
17
17
9
9
42
9
9
9
50
9
0
34
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
9
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
34
9
0
0
0
0
0
17
0
34
34
0
% K
% Leu:
34
0
17
0
0
0
9
0
9
0
0
0
0
0
25
% L
% Met:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
0
0
0
9
0
9
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
9
0
42
0
0
0
9
9
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
34
0
9
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
0
34
0
0
0
0
0
17
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _