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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGH All Species: 23.33
Human Site: S106 Identified Species: 51.33
UniProt: Q14442 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14442 NP_004560.1 188 21081 S106 Q M T S S Y A S G K E S T T F
Chimpanzee Pan troglodytes XP_001136096 204 23369 C106 Q K V I Y Y L C I L L K D P V
Rhesus Macaque Macaca mulatta XP_001107223 188 21161 S106 Q M T S S Y A S G K E S T T F
Dog Lupus familis XP_854339 192 21580 S106 Q M T S S Y A S G K E S T T F
Cat Felis silvestris
Mouse Mus musculus Q5M9N4 188 21059 S106 Q M T S S Y A S G K E S T T F
Rat Rattus norvegicus NP_001102184 188 21220 S106 Q M T S S Y A S G K E S T T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513488 263 28251 S181 Q M T A S Y A S G K E S T T F
Chicken Gallus gallus XP_421190 190 21105 G106 V T S S Y A S G K E S T T F I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002565 181 20430 S102 L G V Q L S S S Y A S G R E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121166 191 22006 F111 Y I E G R R T F C G L N S C E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177880 193 22109 K106 V T G R R V V K F I P F R A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.1 99.4 70.8 N.A. 88.3 91.4 N.A. 45.6 70 N.A. 57.9 N.A. N.A. 25.1 N.A. 32.1
Protein Similarity: 100 58.8 99.4 77.5 N.A. 93.6 94.6 N.A. 53.2 83.6 N.A. 77.6 N.A. N.A. 42.4 N.A. 51.3
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 93.3 13.3 N.A. 6.6 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 40 N.A. 13.3 N.A. N.A. 20 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 55 0 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 10 55 0 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 10 10 0 0 10 0 10 55 % F
% Gly: 0 10 10 10 0 0 0 10 55 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 0 10 10 0 0 0 0 10 % I
% Lys: 0 10 0 0 0 0 0 10 10 55 0 10 0 0 0 % K
% Leu: 10 0 0 0 10 0 10 0 0 10 19 0 0 0 0 % L
% Met: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % P
% Gln: 64 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 19 10 0 0 0 0 0 0 19 0 0 % R
% Ser: 0 0 10 55 55 10 19 64 0 0 19 55 10 0 10 % S
% Thr: 0 19 55 0 0 0 10 0 0 0 0 10 64 55 0 % T
% Val: 19 0 19 0 0 10 10 0 0 0 0 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 19 64 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _