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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GK2 All Species: 27.27
Human Site: S146 Identified Species: 60
UniProt: Q14410 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14410 NP_149991.2 553 60594 S146 S K T G L P L S T Y F S A V K
Chimpanzee Pan troglodytes XP_526574 918 101889 S146 S K T G L P L S T Y F S A V K
Rhesus Macaque Macaca mulatta XP_001090807 553 60686 S146 S K T G L P L S T Y F S A V K
Dog Lupus familis XP_860266 553 60656 S146 S K T G L P L S T Y F S A V K
Cat Felis silvestris
Mouse Mus musculus Q64516 559 61209 S146 S K T G L P L S T Y F S A V K
Rat Rattus norvegicus Q63060 524 57458 S146 S K T G L P L S T Y F S A V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506589 596 65239 S212 S K T G L P I S T Y F S A V K
Chicken Gallus gallus XP_416788 520 57169 K148 S T Y F S A V K L R W L L D N
Frog Xenopus laevis NP_001080640 563 61588 L146 K S R T G L P L S T Y F S A V
Zebra Danio Brachydanio rerio NP_001108056 530 58172 I147 K D K T G L P I S T Y F S A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21944 502 55146 K145 H P Y F S A L K L K W L F Q N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.7 98 88.7 N.A. 87.1 83.3 N.A. 73.6 74.6 77.8 72.3 N.A. N.A. N.A. 44.4 N.A.
Protein Similarity: 100 60 99.6 95.1 N.A. 94.2 90 N.A. 81.7 85.3 87.9 83.9 N.A. N.A. N.A. 63.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 6.6 0 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 20 20 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 19 0 0 0 0 0 0 64 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 19 0 0 0 0 0 0 64 19 10 0 0 % F
% Gly: 0 0 0 64 19 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % I
% Lys: 19 64 10 0 0 0 0 19 0 10 0 0 0 0 64 % K
% Leu: 0 0 0 0 64 19 64 10 19 0 0 19 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % N
% Pro: 0 10 0 0 0 64 19 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 73 10 0 0 19 0 0 64 19 0 0 64 19 0 0 % S
% Thr: 0 10 64 19 0 0 0 0 64 19 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 64 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % W
% Tyr: 0 0 19 0 0 0 0 0 0 64 19 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _