KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F2
All Species:
26.67
Human Site:
Y170
Identified Species:
53.33
UniProt:
Q14209
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14209
NP_004082.1
437
47506
Y170
D
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Chimpanzee
Pan troglodytes
XP_524538
437
47536
Y170
D
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Rhesus Macaque
Macaca mulatta
XP_001102839
437
47573
Y170
D
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Dog
Lupus familis
XP_545361
509
56204
K256
N
K
A
A
E
V
L
K
V
Q
K
R
R
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
P56931
443
48481
Y172
D
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Rat
Rattus norvegicus
Q62814
300
33206
N51
R
R
I
Y
D
I
T
N
V
L
E
G
I
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
R217
E
V
L
E
V
Q
K
R
R
I
Y
D
I
T
N
Chicken
Gallus gallus
Q90977
403
43534
Y145
K
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Frog
Xenopus laevis
NP_001081986
429
46399
K176
N
K
A
A
E
V
L
K
V
Q
K
R
R
I
Y
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
Y171
N
V
Q
K
R
R
L
Y
D
I
T
N
V
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
Y295
H
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
G145
L
L
T
K
R
F
V
G
L
L
R
G
A
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
43
N.A.
83
20.5
N.A.
52.7
40.9
43.9
40
N.A.
20.6
N.A.
N.A.
42.7
Protein Similarity:
100
99.7
98.6
55
N.A.
87.5
34.7
N.A.
62.3
54.9
55.1
55.3
N.A.
31.7
N.A.
N.A.
55.3
P-Site Identity:
100
100
100
0
N.A.
100
0
N.A.
13.3
93.3
0
86.6
N.A.
93.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
100
13.3
N.A.
46.6
93.3
20
100
N.A.
93.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
17
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
9
0
0
0
59
0
0
9
0
9
9
% D
% Glu:
9
0
0
9
17
0
0
0
0
0
9
0
0
0
59
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
17
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
50
0
0
67
0
0
17
17
0
% I
% Lys:
9
17
0
67
0
0
9
17
0
0
17
0
0
0
0
% K
% Leu:
9
9
9
0
0
0
25
0
9
17
0
0
0
59
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
0
0
0
0
0
0
9
0
0
0
59
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
59
0
0
9
0
0
0
17
0
0
0
0
0
% Q
% Arg:
9
9
0
0
67
59
0
9
9
0
9
17
17
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
9
0
0
0
59
0
0
9
0
% T
% Val:
0
67
0
0
9
17
9
0
25
0
0
0
59
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
59
0
0
9
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _