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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F2
All Species:
10.91
Human Site:
T393
Identified Species:
21.82
UniProt:
Q14209
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14209
NP_004082.1
437
47506
T393
E
D
Q
F
L
S
P
T
L
A
C
S
S
P
L
Chimpanzee
Pan troglodytes
XP_524538
437
47536
T393
E
D
Q
F
L
S
P
T
L
A
C
S
S
P
L
Rhesus Macaque
Macaca mulatta
XP_001102839
437
47573
T393
E
D
Q
F
L
S
P
T
L
A
C
S
S
P
L
Dog
Lupus familis
XP_545361
509
56204
L462
E
D
Q
I
P
S
N
L
E
G
P
F
V
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P56931
443
48481
F395
L
Q
Q
T
E
D
Q
F
L
S
P
I
L
A
A
Rat
Rattus norvegicus
Q62814
300
33206
I257
G
S
I
S
G
D
I
I
D
E
L
M
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
Q424
L
L
P
Q
T
E
D
Q
L
V
F
G
G
P
M
Chicken
Gallus gallus
Q90977
403
43534
F358
L
E
H
G
K
D
D
F
P
G
F
L
A
D
E
Frog
Xenopus laevis
NP_001081986
429
46399
L382
E
D
Q
I
S
L
N
L
D
A
P
F
V
N
L
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
Q380
S
L
S
S
I
L
Q
Q
P
E
E
A
I
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
P653
S
Q
R
R
S
D
V
P
M
Y
N
C
A
M
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
S358
D
L
S
A
L
S
R
S
L
L
L
E
T
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
43
N.A.
83
20.5
N.A.
52.7
40.9
43.9
40
N.A.
20.6
N.A.
N.A.
42.7
Protein Similarity:
100
99.7
98.6
55
N.A.
87.5
34.7
N.A.
62.3
54.9
55.1
55.3
N.A.
31.7
N.A.
N.A.
55.3
P-Site Identity:
100
100
100
33.3
N.A.
13.3
6.6
N.A.
13.3
0
33.3
6.6
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
33.3
N.A.
20
6.6
N.A.
20
13.3
33.3
20
N.A.
20
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
34
0
9
17
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
25
9
0
0
0
% C
% Asp:
9
42
0
0
0
34
17
0
17
0
0
0
0
9
17
% D
% Glu:
42
9
0
0
9
9
0
0
9
17
9
9
0
9
17
% E
% Phe:
0
0
0
25
0
0
0
17
0
0
17
17
0
0
9
% F
% Gly:
9
0
0
9
9
0
0
0
0
17
0
9
9
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
17
9
0
9
9
0
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
25
0
0
34
17
0
17
50
9
17
9
9
0
42
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
9
% M
% Asn:
0
0
0
0
0
0
17
0
0
0
9
0
0
17
0
% N
% Pro:
0
0
9
0
9
0
25
9
17
0
25
0
0
42
0
% P
% Gln:
0
17
50
9
0
0
17
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
17
9
17
17
17
42
0
9
0
9
0
25
34
9
0
% S
% Thr:
0
0
0
9
9
0
0
25
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
9
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _