KinATLAS
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PhosphoNET
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DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F2
All Species:
29.09
Human Site:
T173
Identified Species:
58.18
UniProt:
Q14209
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14209
NP_004082.1
437
47506
T173
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
Q
Chimpanzee
Pan troglodytes
XP_524538
437
47536
T173
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
Q
Rhesus Macaque
Macaca mulatta
XP_001102839
437
47573
T173
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
Q
Dog
Lupus familis
XP_545361
509
56204
K259
A
E
V
L
K
V
Q
K
R
R
I
Y
D
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P56931
443
48481
T175
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
Q
Rat
Rattus norvegicus
Q62814
300
33206
E54
Y
D
I
T
N
V
L
E
G
I
D
L
I
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
Y220
E
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Chicken
Gallus gallus
Q90977
403
43534
T148
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
Q
Frog
Xenopus laevis
NP_001081986
429
46399
K179
A
E
V
L
K
V
Q
K
R
R
I
Y
D
I
T
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
T174
K
R
R
L
Y
D
I
T
N
V
L
E
G
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
T298
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
R148
K
R
F
V
G
L
L
R
G
A
P
D
G
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
43
N.A.
83
20.5
N.A.
52.7
40.9
43.9
40
N.A.
20.6
N.A.
N.A.
42.7
Protein Similarity:
100
99.7
98.6
55
N.A.
87.5
34.7
N.A.
62.3
54.9
55.1
55.3
N.A.
31.7
N.A.
N.A.
55.3
P-Site Identity:
100
100
100
6.6
N.A.
100
0
N.A.
6.6
100
6.6
80
N.A.
93.3
N.A.
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
100
20
N.A.
46.6
100
20
100
N.A.
93.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
59
0
0
9
0
9
9
17
0
0
% D
% Glu:
9
17
0
0
0
0
0
9
0
0
0
59
0
9
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
17
0
0
0
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
50
0
0
67
0
0
17
17
0
9
67
0
% I
% Lys:
67
0
0
9
17
0
0
17
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
25
0
9
17
0
0
0
59
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
59
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
17
0
0
0
0
0
0
0
42
% Q
% Arg:
0
67
59
0
9
9
0
9
17
17
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
59
0
0
9
0
0
0
17
% T
% Val:
0
9
17
9
0
25
0
0
0
59
0
0
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
59
0
0
9
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _