KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F2
All Species:
10.91
Human Site:
S406
Identified Species:
21.82
UniProt:
Q14209
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14209
NP_004082.1
437
47506
S406
P
L
I
S
F
S
P
S
L
D
Q
D
D
Y
L
Chimpanzee
Pan troglodytes
XP_524538
437
47536
S406
P
L
I
S
F
S
P
S
L
D
Q
D
D
Y
L
Rhesus Macaque
Macaca mulatta
XP_001102839
437
47573
S406
P
L
I
S
F
S
P
S
L
D
Q
D
D
Y
L
Dog
Lupus familis
XP_545361
509
56204
Q475
N
L
L
P
P
L
L
Q
E
D
Y
L
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P56931
443
48481
S408
A
A
N
S
P
L
I
S
F
S
P
P
L
D
Q
Rat
Rattus norvegicus
Q62814
300
33206
R270
S
D
V
F
P
L
L
R
L
S
P
T
P
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
Q437
P
M
T
G
F
S
P
Q
L
D
H
D
D
Y
L
Chicken
Gallus gallus
Q90977
403
43534
P371
D
E
F
I
A
L
S
P
P
Q
P
Q
D
Y
H
Frog
Xenopus laevis
NP_001081986
429
46399
Q395
N
L
L
P
P
S
M
Q
E
D
Y
L
L
S
L
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
A393
P
F
V
P
L
S
P
A
L
L
S
D
E
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
S666
M
E
G
A
T
T
T
S
A
T
A
D
T
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
D371
E
D
Q
N
G
L
D
D
D
F
V
A
L
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.1
43
N.A.
83
20.5
N.A.
52.7
40.9
43.9
40
N.A.
20.6
N.A.
N.A.
42.7
Protein Similarity:
100
99.7
98.6
55
N.A.
87.5
34.7
N.A.
62.3
54.9
55.1
55.3
N.A.
31.7
N.A.
N.A.
55.3
P-Site Identity:
100
100
100
20
N.A.
13.3
6.6
N.A.
66.6
13.3
26.6
40
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
13.3
13.3
N.A.
73.3
13.3
33.3
66.6
N.A.
26.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
9
0
0
9
9
0
9
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
0
0
0
9
9
9
50
0
50
42
9
9
% D
% Glu:
9
17
0
0
0
0
0
0
17
0
0
0
9
0
0
% E
% Phe:
0
9
9
9
34
0
0
0
9
9
0
0
0
0
0
% F
% Gly:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
25
9
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
42
17
0
9
42
17
0
50
9
0
17
34
0
50
% L
% Met:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
17
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
42
0
0
25
34
0
42
9
9
0
25
9
9
0
9
% P
% Gln:
0
0
9
0
0
0
0
25
0
9
25
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
34
0
50
9
42
0
17
9
0
0
25
0
% S
% Thr:
0
0
9
0
9
9
9
0
0
9
0
9
9
9
0
% T
% Val:
0
0
17
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
17
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _