Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: E2F2 All Species: 15.15
Human Site: S320 Identified Species: 30.3
UniProt: Q14209 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14209 NP_004082.1 437 47506 S320 P S E E P L P S T S T L C P S
Chimpanzee Pan troglodytes XP_524538 437 47536 S320 P S E E P L P S T S T L C P S
Rhesus Macaque Macaca mulatta XP_001102839 437 47573 S320 P S E E P L P S T S T L C P S
Dog Lupus familis XP_545361 509 56204 P389 H L A S T Q G P I E V Y L C P
Cat Felis silvestris
Mouse Mus musculus P56931 443 48481 S322 P A K E A L P S T S A L S P I
Rat Rattus norvegicus Q62814 300 33206 I184 G P I H V L L I N K E S N S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515449 468 50133 Y351 T N G P I E V Y L C P E E G Q
Chicken Gallus gallus Q90977 403 43534 P285 D S S G V C S P V K S P F K A
Frog Xenopus laevis NP_001081986 429 46399 A309 H L S S S Q G A I E V Y L C P
Zebra Danio Brachydanio rerio NP_001074097 429 46452 T307 P I D V F L C T D G G D S G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27368 805 87442 T580 Q E L F S S L T E S S P P T P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123287 404 44387 E285 A P P E T R L E V P D P K E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.1 43 N.A. 83 20.5 N.A. 52.7 40.9 43.9 40 N.A. 20.6 N.A. N.A. 42.7
Protein Similarity: 100 99.7 98.6 55 N.A. 87.5 34.7 N.A. 62.3 54.9 55.1 55.3 N.A. 31.7 N.A. N.A. 55.3
P-Site Identity: 100 100 100 0 N.A. 60 13.3 N.A. 0 6.6 0 20 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 0 N.A. 73.3 13.3 N.A. 6.6 20 6.6 33.3 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 0 9 0 0 9 0 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 9 9 0 0 9 0 0 25 17 0 % C
% Asp: 9 0 9 0 0 0 0 0 9 0 9 9 0 0 0 % D
% Glu: 0 9 25 42 0 9 0 9 9 17 9 9 9 9 0 % E
% Phe: 0 0 0 9 9 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 9 0 9 9 0 0 17 0 0 9 9 0 0 17 0 % G
% His: 17 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 9 0 0 9 17 0 0 0 0 0 9 % I
% Lys: 0 0 9 0 0 0 0 0 0 17 0 0 9 9 0 % K
% Leu: 0 17 9 0 0 50 25 0 9 0 0 34 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 9 0 0 0 9 0 0 % N
% Pro: 42 17 9 9 25 0 34 17 0 9 9 25 9 34 25 % P
% Gln: 9 0 0 0 0 17 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 34 17 17 17 9 9 34 0 42 17 9 17 9 50 % S
% Thr: 9 0 0 0 17 0 0 17 34 0 25 0 0 9 0 % T
% Val: 0 0 0 9 17 0 9 0 17 0 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _