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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FHL2
All Species:
34.85
Human Site:
S140
Identified Species:
63.89
UniProt:
Q14192
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14192
NP_001034581.1
279
32193
S140
Q
Q
P
I
G
T
K
S
F
I
P
K
D
N
Q
Chimpanzee
Pan troglodytes
XP_530486
337
38769
V208
Q
Q
P
M
E
P
R
V
P
L
P
E
E
T
D
Rhesus Macaque
Macaca mulatta
XP_001109260
372
42158
S233
Q
Q
P
I
G
T
K
S
F
I
P
K
D
N
Q
Dog
Lupus familis
XP_531773
424
47549
S285
Q
Q
P
I
G
T
K
S
F
I
P
K
D
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
O70433
279
32054
S140
Q
Q
P
I
G
T
K
S
F
I
P
K
E
N
Q
Rat
Rattus norvegicus
O35115
279
32068
S140
Q
Q
P
I
G
T
K
S
F
I
P
K
E
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511545
328
37179
S189
Q
Q
P
I
G
T
K
S
F
I
P
K
D
N
Q
Chicken
Gallus gallus
XP_416924
279
32412
S140
Q
Q
P
I
G
T
K
S
F
I
P
K
D
N
Q
Frog
Xenopus laevis
Q2TCH4
506
55983
N310
H
T
L
I
G
T
S
N
F
F
E
K
D
G
R
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
G281
K
R
L
L
D
E
G
G
F
F
E
E
K
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648930
559
63656
S418
K
T
A
I
G
T
K
S
F
I
P
R
E
Q
E
Honey Bee
Apis mellifera
XP_393694
798
90528
S657
K
N
P
I
G
T
K
S
F
I
P
R
E
Q
E
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
P213
G
A
E
L
G
Q
R
P
F
F
E
R
N
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.2
74.7
61
N.A.
92.1
91.4
N.A.
67
90.3
20.3
20.5
N.A.
29.8
21.7
20.8
N.A.
Protein Similarity:
100
68.5
74.7
64.3
N.A.
96.7
96.7
N.A.
73.4
95.6
29.6
33.6
N.A.
38.2
27.6
33.6
N.A.
P-Site Identity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
100
100
40
6.6
N.A.
53.3
60
13.3
N.A.
P-Site Similarity:
100
60
100
100
N.A.
100
100
N.A.
100
100
53.3
33.3
N.A.
80
86.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
47
0
8
% D
% Glu:
0
0
8
0
8
8
0
0
0
0
24
16
39
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
93
24
0
0
0
0
0
% F
% Gly:
8
0
0
0
85
0
8
8
0
0
0
0
0
24
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
77
0
0
0
0
0
70
0
0
0
0
0
% I
% Lys:
24
0
0
0
0
0
70
0
0
0
0
62
8
0
0
% K
% Leu:
0
0
16
16
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
8
54
0
% N
% Pro:
0
0
70
0
0
8
0
8
8
0
77
0
0
0
0
% P
% Gln:
62
62
0
0
0
8
0
0
0
0
0
0
0
16
54
% Q
% Arg:
0
8
0
0
0
0
16
0
0
0
0
24
0
0
16
% R
% Ser:
0
0
0
0
0
0
8
70
0
0
0
0
0
0
8
% S
% Thr:
0
16
0
0
0
77
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _