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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
8.79
Human Site:
Y413
Identified Species:
17.58
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
Y413
E
Q
Q
S
Q
E
E
Y
L
S
D
I
A
Y
K
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
Y413
E
Q
Q
A
Q
E
E
Y
L
S
D
T
A
Y
K
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
Y413
E
Q
Q
A
Q
E
K
Y
L
S
D
I
A
Y
K
Dog
Lupus familis
XP_539984
1680
188955
N611
V
G
N
K
L
K
T
N
T
E
R
I
C
L
M
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
E379
I
E
D
N
L
L
R
E
D
M
E
R
T
C
V
Rat
Rattus norvegicus
XP_001059940
1400
157256
E379
M
E
D
S
L
L
R
E
V
M
E
R
T
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
R772
R
C
I
D
N
M
D
R
I
C
L
M
S
L
D
Chicken
Gallus gallus
Q9I920
1142
126164
L192
S
T
I
R
N
Q
T
L
D
K
L
D
T
S
Y
Frog
Xenopus laevis
O93530
1436
161833
Q381
E
R
E
D
D
K
K
Q
T
N
P
D
Y
K
L
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
I336
E
C
A
M
S
L
D
I
S
E
Y
E
L
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
F106
D
Q
G
D
D
C
E
F
I
P
A
C
D
E
T
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
N324
R
H
D
K
D
Q
F
N
D
I
R
A
K
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
86.6
86.6
6.6
N.A.
0
6.6
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
93.3
100
13.3
N.A.
20
26.6
N.A.
26.6
6.6
40
13.3
N.A.
N.A.
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
0
0
0
0
0
9
9
25
0
0
% A
% Cys:
0
17
0
0
0
9
0
0
0
9
0
9
9
17
0
% C
% Asp:
9
0
25
25
25
0
17
0
25
0
25
17
9
0
9
% D
% Glu:
42
17
9
0
0
25
25
17
0
17
17
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
17
0
0
0
0
9
17
9
0
25
0
0
0
% I
% Lys:
0
0
0
17
0
17
17
0
0
9
0
0
9
9
25
% K
% Leu:
0
0
0
0
25
25
0
9
25
0
17
0
9
25
17
% L
% Met:
9
0
0
9
0
9
0
0
0
17
0
9
0
0
17
% M
% Asn:
0
0
9
9
17
0
0
17
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% P
% Gln:
0
34
25
0
25
17
0
9
0
0
0
0
0
9
0
% Q
% Arg:
17
9
0
9
0
0
17
9
0
0
17
17
0
0
9
% R
% Ser:
9
0
0
17
9
0
0
0
9
25
0
0
9
9
0
% S
% Thr:
0
9
0
0
0
0
17
0
17
0
0
9
25
0
9
% T
% Val:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
0
9
0
9
25
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _