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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
30.61
Human Site:
T1193
Identified Species:
61.21
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
T1193
D
M
A
K
M
R
P
T
T
V
E
N
V
K
R
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
T1193
D
M
A
K
M
R
P
T
T
V
E
N
V
K
R
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
T1193
D
M
A
K
M
R
P
T
T
V
E
N
I
K
R
Dog
Lupus familis
XP_539984
1680
188955
T1391
E
M
A
K
M
R
P
T
T
F
E
N
M
K
R
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
T1158
D
M
A
K
M
R
P
T
T
V
E
N
M
K
Q
Rat
Rattus norvegicus
XP_001059940
1400
157256
T1158
D
M
A
K
M
R
P
T
T
V
E
N
V
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
T1544
D
M
A
K
M
R
P
T
S
V
Q
N
L
I
T
Chicken
Gallus gallus
Q9I920
1142
126164
L914
A
Q
A
V
L
N
G
L
L
Q
V
E
F
H
E
Frog
Xenopus laevis
O93530
1436
161833
T1141
D
M
A
K
L
R
P
T
T
S
E
N
M
K
K
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
P1133
L
D
M
S
K
L
R
P
C
T
M
S
S
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
E828
V
G
I
A
N
M
H
E
V
A
P
F
Q
I
V
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
D555
E
F
I
S
V
A
T
D
L
I
E
D
V
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
100
93.3
80
N.A.
86.6
93.3
N.A.
66.6
6.6
73.3
0
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
13.3
93.3
13.3
N.A.
N.A.
N.A.
0
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
75
9
0
9
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
59
9
0
0
0
0
0
9
0
0
0
9
0
0
0
% D
% Glu:
17
0
0
0
0
0
0
9
0
0
67
9
0
0
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
9
9
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
17
0
0
0
0
0
0
9
0
0
9
17
0
% I
% Lys:
0
0
0
67
9
0
0
0
0
0
0
0
0
59
17
% K
% Leu:
9
0
0
0
17
9
0
9
17
0
0
0
9
9
0
% L
% Met:
0
67
9
0
59
9
0
0
0
0
9
0
25
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
0
0
0
0
0
67
9
0
0
9
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
9
0
9
9
17
% Q
% Arg:
0
0
0
0
0
67
9
0
0
0
0
0
0
0
42
% R
% Ser:
0
0
0
17
0
0
0
0
9
9
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
9
67
59
9
0
0
0
0
9
% T
% Val:
9
0
0
9
9
0
0
0
9
50
9
0
34
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _