KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
22.42
Human Site:
S759
Identified Species:
44.85
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
S759
P
F
L
V
K
T
S
S
H
W
E
F
E
G
P
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
S759
P
F
L
V
K
T
S
S
H
W
E
F
E
G
P
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
S759
F
L
V
K
T
T
S
S
H
W
E
F
E
G
P
Dog
Lupus familis
XP_539984
1680
188955
S956
F
L
V
Q
K
T
S
S
I
W
E
F
E
G
P
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
S724
F
L
V
R
K
A
S
S
A
W
E
F
E
G
P
Rat
Rattus norvegicus
XP_001059940
1400
157256
S724
F
L
V
R
K
T
S
S
A
W
E
F
E
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
S1114
F
L
V
K
K
T
G
S
V
L
E
F
E
G
P
Chicken
Gallus gallus
Q9I920
1142
126164
L507
V
C
A
S
N
R
L
L
S
A
L
E
N
L
Y
Frog
Xenopus laevis
O93530
1436
161833
S702
L
I
K
K
Q
Q
G
S
G
W
E
F
E
G
A
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
G655
F
L
V
K
K
K
G
G
G
Y
E
F
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
V421
R
K
N
L
Y
I
S
V
H
S
S
K
D
M
A
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
G639
I
S
L
S
G
C
R
G
T
M
N
S
G
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
100
66.6
66.6
N.A.
60
66.6
N.A.
53.3
0
40
33.3
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
73.3
73.3
N.A.
66.6
73.3
N.A.
60
0
46.6
46.6
N.A.
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
0
17
9
0
0
0
0
17
% A
% Cys:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
75
9
75
0
0
% E
% Phe:
50
17
0
0
0
0
0
0
0
0
0
75
0
0
0
% F
% Gly:
0
0
0
0
9
0
25
17
17
0
0
0
9
75
0
% G
% His:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
9
0
0
9
0
0
0
0
9
0
% I
% Lys:
0
9
9
34
59
9
0
0
0
0
0
9
0
0
0
% K
% Leu:
9
50
25
9
0
0
9
9
0
9
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% P
% Gln:
0
0
0
9
9
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
17
0
9
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
17
0
0
59
67
9
9
9
9
0
0
17
% S
% Thr:
0
0
0
0
9
50
0
0
9
0
0
0
0
0
0
% T
% Val:
9
0
50
17
0
0
0
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _