KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
16.67
Human Site:
S1256
Identified Species:
33.33
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
S1256
K
N
K
I
C
T
L
S
Q
S
M
A
I
T
Y
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
S1256
K
N
K
I
C
T
L
S
Q
S
M
A
I
T
Y
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
S1256
K
N
K
I
C
T
L
S
Q
S
M
A
I
T
Y
Dog
Lupus familis
XP_539984
1680
188955
S1454
E
N
E
T
C
S
L
S
Q
S
A
A
I
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
P1221
E
K
K
D
C
S
L
P
Q
S
V
A
V
T
Y
Rat
Rattus norvegicus
XP_001059940
1400
157256
P1221
E
N
K
A
C
S
L
P
Q
S
A
A
V
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
S1606
K
E
V
Y
S
S
L
S
P
S
E
A
I
T
Y
Chicken
Gallus gallus
Q9I920
1142
126164
S972
V
H
Y
F
N
I
F
S
T
S
T
L
K
K
I
Frog
Xenopus laevis
O93530
1436
161833
P1204
E
Q
E
R
I
S
L
P
E
S
Q
R
M
S
Y
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
V1191
H
S
S
R
E
S
V
V
G
S
V
A
Q
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
A886
F
S
K
E
T
G
I
A
T
N
V
N
A
N
D
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
M573
L
T
A
T
A
T
P
M
V
Q
K
D
I
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
100
100
66.6
N.A.
53.3
60
N.A.
53.3
13.3
20
13.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
60
20
60
40
N.A.
N.A.
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
0
0
9
0
0
17
67
9
0
0
% A
% Cys:
0
0
0
0
50
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
9
% D
% Glu:
34
9
17
9
9
0
0
0
9
0
9
0
0
0
0
% E
% Phe:
9
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
25
9
9
9
0
0
0
0
0
50
0
9
% I
% Lys:
34
9
50
0
0
0
0
0
0
0
9
0
9
9
0
% K
% Leu:
9
0
0
0
0
0
67
0
0
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
25
0
9
0
0
% M
% Asn:
0
42
0
0
9
0
0
0
0
9
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
9
25
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
50
9
9
0
9
0
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
9
% R
% Ser:
0
17
9
0
9
50
0
50
0
84
0
0
0
9
0
% S
% Thr:
0
9
0
17
9
34
0
0
17
0
9
0
0
59
0
% T
% Val:
9
0
9
0
0
0
9
9
9
0
25
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _