KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WRN
All Species:
16.97
Human Site:
S1133
Identified Species:
33.94
UniProt:
Q14191
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14191
NP_000544.2
1432
162495
S1133
K
K
S
I
M
V
Q
S
P
E
K
A
Y
S
S
Chimpanzee
Pan troglodytes
XP_528104
1432
162383
S1133
K
K
S
I
M
V
Q
S
P
E
K
A
Y
S
S
Rhesus Macaque
Macaca mulatta
XP_001085031
1432
162219
A1133
K
K
S
I
M
V
Q
A
P
E
K
S
Y
S
S
Dog
Lupus familis
XP_539984
1680
188955
S1331
E
K
S
I
I
V
H
S
P
G
K
S
Y
K
S
Cat
Felis silvestris
Mouse
Mus musculus
O09053
1401
157269
S1098
K
K
S
A
V
M
P
S
P
G
T
S
S
S
P
Rat
Rattus norvegicus
XP_001059940
1400
157256
S1098
K
K
S
V
V
M
Q
S
P
G
T
S
Y
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508312
1813
203868
P1488
M
M
Q
L
L
P
E
P
Y
K
S
A
K
T
A
Chicken
Gallus gallus
Q9I920
1142
126164
G862
K
I
H
S
G
I
F
G
K
G
A
A
Y
S
R
Frog
Xenopus laevis
O93530
1436
161833
T1081
K
S
S
F
K
L
Q
T
P
C
K
L
S
R
P
Zebra Danio
Brachydanio rerio
XP_697980
1361
152386
A1081
Q
I
Q
T
D
V
R
A
Q
T
P
G
A
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19546
1056
118504
I776
S
T
E
I
P
T
K
I
L
G
A
N
K
I
R
Sea Urchin
Strong. purpuratus
XP_001184484
1274
143807
L994
V
I
S
P
L
I
S
L
M
E
D
Q
V
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.1
64.5
N.A.
70.2
69.5
N.A.
41.7
22.9
52.1
45.8
N.A.
N.A.
N.A.
25.4
20.3
Protein Similarity:
100
99.3
97.2
72.6
N.A.
81.8
81.2
N.A.
56.5
38.3
70
63.7
N.A.
N.A.
N.A.
41.8
38.8
P-Site Identity:
100
100
86.6
60
N.A.
40
60
N.A.
6.6
26.6
33.3
13.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
80
N.A.
60
86.6
N.A.
46.6
33.3
46.6
40
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
17
0
0
17
34
9
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
9
0
9
0
0
0
9
0
0
34
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
42
0
9
0
0
0
% G
% His:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
42
9
17
0
9
0
0
0
0
0
9
0
% I
% Lys:
59
50
0
0
9
0
9
0
9
9
42
0
17
9
0
% K
% Leu:
0
0
0
9
17
9
0
9
9
0
0
9
0
0
0
% L
% Met:
9
9
0
0
25
17
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
9
9
9
9
9
59
0
9
0
0
0
17
% P
% Gln:
9
0
17
0
0
0
42
0
9
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
17
% R
% Ser:
9
9
67
9
0
0
9
42
0
0
9
34
17
59
42
% S
% Thr:
0
9
0
9
0
9
0
9
0
9
17
0
0
9
0
% T
% Val:
9
0
0
9
17
42
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _