KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK1
All Species:
17.27
Human Site:
T443
Identified Species:
47.5
UniProt:
Q14185
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14185
NP_001371.1
1865
215346
T443
D
F
D
K
G
S
K
T
T
A
K
N
V
E
V
Chimpanzee
Pan troglodytes
XP_001160237
1849
212681
K440
E
F
D
K
G
K
K
K
T
P
K
N
V
E
V
Rhesus Macaque
Macaca mulatta
XP_001107224
1870
215340
K461
E
F
D
K
G
K
K
K
T
P
K
N
V
E
V
Dog
Lupus familis
XP_544064
1858
214527
T433
D
F
D
K
G
S
K
T
T
A
K
N
V
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUR4
1865
215067
T443
D
F
D
K
G
S
K
T
T
A
K
N
V
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508993
1829
212107
T435
D
F
D
K
Y
N
K
T
T
Q
R
N
V
E
V
Chicken
Gallus gallus
XP_417678
1877
216176
K461
E
F
D
K
G
K
K
K
T
P
K
N
V
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103481
1866
215254
T442
D
F
D
K
G
S
K
T
T
P
K
N
V
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785550
1874
216318
P445
D
F
D
R
G
A
R
P
K
A
R
N
V
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.6
64.5
97.3
N.A.
96.4
N.A.
N.A.
59.3
65.5
N.A.
84.3
N.A.
N.A.
N.A.
N.A.
48.6
Protein Similarity:
100
79.1
78.9
98.6
N.A.
98.2
N.A.
N.A.
74.8
79.5
N.A.
92.2
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
73.3
73.3
100
N.A.
100
N.A.
N.A.
73.3
73.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
80
80
100
N.A.
100
N.A.
N.A.
86.6
80
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
45
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
34
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% E
% Phe:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
89
0
34
89
34
12
0
78
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
100
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
45
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
12
0
0
0
23
0
0
0
0
% R
% Ser:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
56
89
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _