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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOCK1
All Species:
24.55
Human Site:
S245
Identified Species:
67.5
UniProt:
Q14185
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14185
NP_001371.1
1865
215346
S245
E
D
A
E
V
L
M
S
L
Y
D
P
V
E
S
Chimpanzee
Pan troglodytes
XP_001160237
1849
212681
A244
E
D
A
E
L
F
M
A
L
Y
D
P
D
Q
S
Rhesus Macaque
Macaca mulatta
XP_001107224
1870
215340
A244
E
D
A
E
L
F
M
A
L
Y
D
P
D
Q
S
Dog
Lupus familis
XP_544064
1858
214527
S235
E
D
A
E
V
L
M
S
L
Y
D
P
V
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUR4
1865
215067
S245
E
D
A
E
V
L
M
S
L
Y
D
P
M
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508993
1829
212107
S237
E
D
A
E
L
F
M
S
L
Y
D
P
N
K
Q
Chicken
Gallus gallus
XP_417678
1877
216176
S244
E
D
A
E
L
L
M
S
L
Y
D
P
D
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103481
1866
215254
S244
E
D
A
E
V
L
M
S
L
Y
D
P
I
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785550
1874
216318
S246
E
N
S
E
V
M
M
S
L
Y
D
G
K
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.6
64.5
97.3
N.A.
96.4
N.A.
N.A.
59.3
65.5
N.A.
84.3
N.A.
N.A.
N.A.
N.A.
48.6
Protein Similarity:
100
79.1
78.9
98.6
N.A.
98.2
N.A.
N.A.
74.8
79.5
N.A.
92.2
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
66.6
66.6
100
N.A.
93.3
N.A.
N.A.
66.6
80
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
N.A.
N.A.
80
86.6
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
89
0
0
0
0
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
89
0
0
0
0
0
0
0
0
100
0
34
0
0
% D
% Glu:
100
0
0
100
0
0
0
0
0
0
0
0
0
45
0
% E
% Phe:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% K
% Leu:
0
0
0
0
45
56
0
0
100
0
0
0
0
23
0
% L
% Met:
0
0
0
0
0
12
100
0
0
0
0
0
12
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
89
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
0
0
0
0
78
0
0
0
0
0
0
78
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
56
0
0
0
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _