Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOCK1 All Species: 16.06
Human Site: S1664 Identified Species: 44.17
UniProt: Q14185 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14185 NP_001371.1 1865 215346 S1664 S T P S R P G S D G F A L E P
Chimpanzee Pan troglodytes XP_001160237 1849 212681 L1638 S R T G S I V L P Y I M S S T
Rhesus Macaque Macaca mulatta XP_001107224 1870 215340 Y1661 T G S I V L P Y I M S S T L R
Dog Lupus familis XP_544064 1858 214527 S1654 S T P S R P G S D G F A L E P
Cat Felis silvestris
Mouse Mus musculus Q8BUR4 1865 215067 S1664 S T P S R P G S D G F A L E P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508993 1829 212107 R1636 R S M L R S Y R Q M S I I S L
Chicken Gallus gallus XP_417678 1877 216176 S1667 V L P Y I M S S T L R R L S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103481 1866 215254 S1661 N S P S R P G S D G F A L E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785550 1874 216318 S1673 S D T Q G S R S S I I S N P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 64.5 97.3 N.A. 96.4 N.A. N.A. 59.3 65.5 N.A. 84.3 N.A. N.A. N.A. N.A. 48.6
Protein Similarity: 100 79.1 78.9 98.6 N.A. 98.2 N.A. N.A. 74.8 79.5 N.A. 92.2 N.A. N.A. N.A. N.A. 67.1
P-Site Identity: 100 6.6 0 100 N.A. 100 N.A. N.A. 6.6 20 N.A. 86.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 6.6 13.3 100 N.A. 100 N.A. N.A. 20 20 N.A. 100 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 0 0 45 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 45 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 % F
% Gly: 0 12 0 12 12 0 45 0 0 45 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 12 12 0 0 12 12 23 12 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 12 0 12 0 12 0 12 0 0 56 12 12 % L
% Met: 0 0 12 0 0 12 0 0 0 23 0 12 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % N
% Pro: 0 0 56 0 0 45 12 0 12 0 0 0 0 12 45 % P
% Gln: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % Q
% Arg: 12 12 0 0 56 0 12 12 0 0 12 12 0 0 12 % R
% Ser: 56 23 12 45 12 23 12 67 12 0 23 23 12 34 0 % S
% Thr: 12 34 23 0 0 0 0 0 12 0 0 0 12 0 12 % T
% Val: 12 0 0 0 12 0 12 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 12 12 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _