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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOCK1 All Species: 15.45
Human Site: S1646 Identified Species: 42.5
UniProt: Q14185 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14185 NP_001371.1 1865 215346 S1646 P S S S R P L S V A S V S S L
Chimpanzee Pan troglodytes XP_001160237 1849 212681 T1620 E K H Y G V I T L P P N L T E
Rhesus Macaque Macaca mulatta XP_001107224 1870 215340 P1643 H Y G V I T L P P N L R E R K
Dog Lupus familis XP_544064 1858 214527 S1636 P S S S R P L S V A S V S S L
Cat Felis silvestris
Mouse Mus musculus Q8BUR4 1865 215067 S1646 P S S S R P L S V A S V S S F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508993 1829 212107 P1618 E Y G V R E L P D F D D R R V
Chicken Gallus gallus XP_417678 1877 216176 T1649 I T L P P S L T E R K P S R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103481 1866 215254 S1643 P S S Q R P L S V A S V T S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785550 1874 216318 P1655 G Q T Y S G R P L S S M S T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 64.5 97.3 N.A. 96.4 N.A. N.A. 59.3 65.5 N.A. 84.3 N.A. N.A. N.A. N.A. 48.6
Protein Similarity: 100 79.1 78.9 98.6 N.A. 98.2 N.A. N.A. 74.8 79.5 N.A. 92.2 N.A. N.A. N.A. N.A. 67.1
P-Site Identity: 100 0 6.6 100 N.A. 93.3 N.A. N.A. 13.3 13.3 N.A. 86.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 6.6 100 N.A. 93.3 N.A. N.A. 20 26.6 N.A. 93.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 12 0 12 12 0 0 0 % D
% Glu: 23 0 0 0 0 12 0 0 12 0 0 0 12 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 12 % F
% Gly: 12 0 23 0 12 12 0 0 0 0 0 0 0 0 0 % G
% His: 12 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 12 0 12 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 12 0 0 0 12 % K
% Leu: 0 0 12 0 0 0 78 0 23 0 12 0 12 0 34 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 0 % N
% Pro: 45 0 0 12 12 45 0 34 12 12 12 12 0 0 0 % P
% Gln: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 56 0 12 0 0 12 0 12 12 34 0 % R
% Ser: 0 45 45 34 12 12 0 45 0 12 56 0 56 45 23 % S
% Thr: 0 12 12 0 0 12 0 23 0 0 0 0 12 23 0 % T
% Val: 0 0 0 23 0 12 0 0 45 0 0 45 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 0 23 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _