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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA2
All Species:
19.7
Human Site:
S75
Identified Species:
30.95
UniProt:
Q14181
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14181
NP_002680.2
598
65948
S75
E
F
L
S
K
R
L
S
K
A
R
H
S
T
C
Chimpanzee
Pan troglodytes
XP_508549
598
65915
S75
E
F
L
S
K
R
L
S
K
A
R
H
S
T
C
Rhesus Macaque
Macaca mulatta
XP_001113977
598
65971
S75
E
F
L
S
K
R
L
S
K
A
R
H
S
A
C
Dog
Lupus familis
XP_533234
595
65743
S71
S
F
E
H
E
C
L
S
K
K
L
S
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P33611
600
66249
S75
E
V
L
N
K
K
L
S
K
A
W
H
S
A
S
Rat
Rattus norvegicus
O89043
600
66618
S75
E
V
L
N
K
K
L
S
K
A
C
H
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519697
439
48232
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086972
598
66827
A75
E
V
L
N
K
K
S
A
R
P
R
P
S
L
K
Zebra Danio
Brachydanio rerio
NP_955875
599
66656
K76
E
V
L
N
K
K
K
K
P
K
S
T
S
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB62
609
66952
R72
E
R
K
V
L
Q
L
R
K
D
K
A
G
Y
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21625
581
64085
D62
N
L
G
Q
K
S
V
D
S
G
I
L
A
K
L
Sea Urchin
Strong. purpuratus
XP_780208
604
66528
S79
E
T
L
S
K
K
S
S
K
V
K
T
P
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130410
626
69135
N77
G
F
L
S
H
L
Q
N
E
V
K
D
R
I
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176930
620
69024
E78
H
L
Q
N
E
Q
K
E
S
I
M
R
V
E
E
Baker's Yeast
Sacchar. cerevisiae
P38121
705
78756
K74
F
L
Q
L
Q
M
E
K
R
A
N
Q
I
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.1
88.1
N.A.
83
84.3
N.A.
57.8
N.A.
64.8
57.4
N.A.
29.8
N.A.
25.5
43.3
Protein Similarity:
100
100
98.4
93.8
N.A.
90.1
91
N.A.
66.7
N.A.
80
75.2
N.A.
49.4
N.A.
47.6
62.9
P-Site Identity:
100
100
93.3
26.6
N.A.
60
60
N.A.
0
N.A.
33.3
26.6
N.A.
20
N.A.
6.6
40
P-Site Similarity:
100
100
93.3
33.3
N.A.
73.3
73.3
N.A.
0
N.A.
60
40
N.A.
33.3
N.A.
20
60
Percent
Protein Identity:
N.A.
28.5
N.A.
30.3
25.1
N.A.
Protein Similarity:
N.A.
47.4
N.A.
50
43.4
N.A.
P-Site Identity:
N.A.
20
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
40
0
7
7
27
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
20
% C
% Asp:
0
0
0
0
0
0
0
7
0
7
0
7
0
0
0
% D
% Glu:
60
0
7
0
14
0
7
7
7
0
0
0
0
7
7
% E
% Phe:
7
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
7
0
0
0
0
0
0
7
0
0
7
0
7
% G
% His:
7
0
0
7
7
0
0
0
0
0
0
34
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
7
0
7
7
7
% I
% Lys:
0
0
7
0
60
34
14
14
54
14
20
0
0
14
14
% K
% Leu:
0
20
60
7
7
7
47
0
0
0
7
7
0
7
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
34
0
0
0
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
7
0
7
7
0
7
% P
% Gln:
0
0
14
7
7
14
7
0
0
0
0
7
0
0
0
% Q
% Arg:
0
7
0
0
0
20
0
7
14
0
27
7
14
0
0
% R
% Ser:
7
0
0
34
0
7
14
47
14
0
7
7
47
14
27
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
0
14
0
14
0
% T
% Val:
0
27
0
7
0
0
7
0
0
14
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _