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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
0.3
Human Site:
Y72
Identified Species:
0.48
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
Y72
P
M
K
Y
M
L
K
Y
F
G
A
H
E
R
L
Chimpanzee
Pan troglodytes
XP_511538
656
72549
L152
E
S
P
I
V
R
S
L
A
K
A
H
E
R
L
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
N79
D
S
I
S
I
F
N
N
G
R
A
H
E
R
L
Dog
Lupus familis
XP_548068
552
61535
N66
K
L
E
A
V
R
D
N
N
L
E
L
V
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
N66
K
L
E
A
V
R
D
N
N
L
E
L
V
Q
E
Rat
Rattus norvegicus
Q62915
909
103240
F219
L
L
S
G
C
L
P
F
Y
G
T
K
E
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
D66
L
V
N
E
I
L
E
D
I
S
P
L
V
N
V
Chicken
Gallus gallus
Q5ZJ00
468
52501
P42
P
E
A
I
A
Q
A
P
N
A
M
T
E
D
I
Frog
Xenopus laevis
NP_001087762
532
59489
T68
V
R
D
S
S
G
I
T
A
E
L
Q
A
I
L
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
A85
D
L
T
E
E
L
Q
A
R
S
A
S
N
E
I
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
Q41
Q
N
K
P
T
D
K
Q
A
A
M
Q
T
Y
E
Fruit Fly
Dros. melanogaster
Q24210
898
100893
R286
R
D
R
D
K
L
Q
R
T
H
L
A
D
T
V
Honey Bee
Apis mellifera
XP_391909
602
67965
D104
K
V
Q
E
R
L
E
D
P
P
L
H
V
E
P
Nematode Worm
Caenorhab. elegans
P54936
961
108794
F225
L
L
A
G
R
L
P
F
S
G
S
T
S
D
I
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
L71
K
P
H
R
M
D
S
L
G
L
A
A
D
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
33.3
33.3
0
N.A.
0
33.3
N.A.
6.6
13.3
6.6
13.3
13.3
6.6
13.3
13.3
13.3
P-Site Similarity:
100
40
40
26.6
N.A.
26.6
53.3
N.A.
33.3
20
6.6
33.3
13.3
33.3
33.3
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
7
0
7
7
20
14
34
14
7
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
7
7
0
14
14
14
0
0
0
0
14
14
0
% D
% Glu:
7
7
14
20
7
0
14
0
0
7
14
0
34
14
20
% E
% Phe:
0
0
0
0
0
7
0
14
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
14
0
7
0
0
14
20
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
7
0
27
0
0
0
% H
% Ile:
0
0
7
14
14
0
7
0
7
0
0
0
0
14
20
% I
% Lys:
27
0
14
0
7
0
14
0
0
7
0
7
0
0
0
% K
% Leu:
20
34
0
0
0
47
0
14
0
20
20
20
0
0
34
% L
% Met:
0
7
0
0
14
0
0
0
0
0
14
0
0
0
7
% M
% Asn:
0
7
7
0
0
0
7
20
20
0
0
0
7
7
0
% N
% Pro:
14
7
7
7
0
0
14
7
7
7
7
0
0
0
7
% P
% Gln:
7
0
7
0
0
7
14
7
0
0
0
14
0
14
0
% Q
% Arg:
7
7
7
7
14
20
0
7
7
7
0
0
0
27
0
% R
% Ser:
0
14
7
14
7
0
14
0
7
14
7
7
7
0
0
% S
% Thr:
0
0
7
0
7
0
0
7
7
0
7
14
7
7
0
% T
% Val:
7
14
0
0
20
0
0
0
0
0
0
0
27
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _