KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
30.91
Human Site:
Y539
Identified Species:
48.57
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
Y539
I
Q
R
G
Y
G
H
Y
F
D
L
C
L
V
N
Chimpanzee
Pan troglodytes
XP_511538
656
72549
Y619
I
Q
R
G
Y
G
H
Y
F
D
L
C
L
V
N
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y545
I
Q
R
A
Y
N
H
Y
F
D
L
I
I
I
N
Dog
Lupus familis
XP_548068
552
61535
Y515
I
Q
R
G
Y
G
H
Y
F
D
L
S
L
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
Y515
I
Q
R
G
Y
G
H
Y
F
D
L
S
L
V
N
Rat
Rattus norvegicus
Q62915
909
103240
Y872
L
Q
R
T
Y
A
H
Y
F
D
L
T
I
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
Y503
I
Q
R
A
Y
N
H
Y
F
D
L
I
I
I
N
Chicken
Gallus gallus
Q5ZJ00
468
52501
F432
R
S
R
Y
A
H
Y
F
D
L
S
I
V
N
N
Frog
Xenopus laevis
NP_001087762
532
59489
Y495
V
Q
Q
A
Y
G
H
Y
F
D
L
T
L
V
N
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
L538
M
E
N
Q
Y
G
H
L
F
E
K
V
I
V
N
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
F431
L
N
T
Y
R
Q
Y
F
D
V
V
L
V
N
N
Fruit Fly
Dros. melanogaster
Q24210
898
100893
F861
L
R
Q
L
Y
G
H
F
F
D
L
T
I
V
N
Honey Bee
Apis mellifera
XP_391909
602
67965
Y565
L
Q
R
A
Y
E
K
Y
I
D
L
V
I
V
N
Nematode Worm
Caenorhab. elegans
P54936
961
108794
L924
L
R
Q
A
F
G
H
L
F
D
F
I
I
T
N
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
L516
I
E
R
Q
Y
S
H
L
F
D
F
T
I
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
66.6
93.3
N.A.
93.3
60
N.A.
66.6
13.3
73.3
40
6.6
53.3
53.3
33.3
53.3
P-Site Similarity:
100
100
80
93.3
N.A.
93.3
80
N.A.
80
33.3
86.6
66.6
40
86.6
66.6
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
7
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
14
80
0
0
0
0
0
% D
% Glu:
0
14
0
0
0
7
0
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
20
80
0
14
0
0
0
0
% F
% Gly:
0
0
0
27
0
54
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
80
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
0
0
0
0
0
0
7
0
0
27
54
20
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% K
% Leu:
34
0
0
7
0
0
0
20
0
7
67
7
34
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
14
0
0
0
0
0
0
0
14
100
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
60
20
14
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
14
67
0
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
7
0
0
0
0
7
14
0
0
0
% S
% Thr:
0
0
7
7
0
0
0
0
0
0
0
27
0
7
0
% T
% Val:
7
0
0
0
0
0
0
0
0
7
7
14
14
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
80
0
14
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _