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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
30
Human Site:
Y440
Identified Species:
47.14
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
Y440
A
D
V
R
A
G
R
Y
L
E
H
G
E
Y
E
Chimpanzee
Pan troglodytes
XP_511538
656
72549
Y520
A
D
I
R
A
G
R
Y
L
E
H
G
E
Y
E
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y446
A
D
I
K
A
G
K
Y
L
E
H
G
E
Y
E
Dog
Lupus familis
XP_548068
552
61535
Y416
A
D
I
R
A
G
R
Y
L
E
H
G
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
Y416
A
D
I
R
A
G
R
Y
L
E
H
G
E
Y
E
Rat
Rattus norvegicus
Q62915
909
103240
F773
E
N
G
K
N
Y
Y
F
V
S
H
D
Q
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
Y404
T
D
V
K
A
G
R
Y
L
E
H
G
E
Y
E
Chicken
Gallus gallus
Q5ZJ00
468
52501
R343
V
S
T
E
E
M
T
R
D
I
S
A
N
E
F
Frog
Xenopus laevis
NP_001087762
532
59489
Y396
Q
D
I
K
A
G
R
Y
L
E
H
G
E
Y
E
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
F434
A
D
I
Q
N
N
K
F
I
E
H
G
E
Y
K
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
K342
I
S
N
E
A
M
T
K
C
I
S
A
N
E
L
Fruit Fly
Dros. melanogaster
Q24210
898
100893
I772
H
D
E
M
M
A
D
I
G
A
N
E
Y
L
E
Honey Bee
Apis mellifera
XP_391909
602
67965
Y465
T
D
I
R
E
H
R
Y
L
E
Y
G
E
H
G
Nematode Worm
Caenorhab. elegans
P54936
961
108794
F825
V
D
G
K
H
Y
Y
F
V
T
N
E
Q
M
M
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
F420
Q
D
I
L
N
H
N
F
L
E
Y
G
D
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
93.3
80
93.3
N.A.
93.3
6.6
N.A.
86.6
0
80
46.6
6.6
13.3
53.3
6.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
93.3
0
93.3
86.6
6.6
20
73.3
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
54
7
0
0
0
7
0
14
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
80
0
0
0
0
7
0
7
0
0
7
7
0
0
% D
% Glu:
7
0
7
14
14
0
0
0
0
67
0
14
60
14
54
% E
% Phe:
0
0
0
0
0
0
0
27
0
0
0
0
0
7
7
% F
% Gly:
0
0
14
0
0
47
0
0
7
0
0
67
0
0
7
% G
% His:
7
0
0
0
7
14
0
0
0
0
60
0
0
7
0
% H
% Ile:
7
0
54
0
0
0
0
7
7
14
0
0
0
0
0
% I
% Lys:
0
0
0
34
0
0
14
7
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
7
0
0
0
0
60
0
0
0
0
7
7
% L
% Met:
0
0
0
7
7
14
0
0
0
0
0
0
0
14
14
% M
% Asn:
0
7
7
0
20
7
7
0
0
0
14
0
14
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
7
0
0
0
0
0
0
0
0
14
0
0
% Q
% Arg:
0
0
0
34
0
0
47
7
0
0
0
0
0
0
0
% R
% Ser:
0
14
0
0
0
0
0
0
0
7
14
0
0
0
0
% S
% Thr:
14
0
7
0
0
0
14
0
0
7
0
0
0
0
0
% T
% Val:
14
0
14
0
0
0
0
0
14
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
14
54
0
0
14
0
7
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _