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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
25.76
Human Site:
T499
Identified Species:
40.48
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
T499
I
E
A
P
D
F
E
T
L
R
A
M
N
R
A
Chimpanzee
Pan troglodytes
XP_511538
656
72549
T579
I
E
A
P
D
F
E
T
L
R
A
M
N
R
A
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
T505
I
A
A
P
E
L
E
T
L
R
A
M
H
K
A
Dog
Lupus familis
XP_548068
552
61535
T475
I
E
A
P
D
F
E
T
L
R
A
M
N
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
T475
I
E
A
P
D
Y
E
T
L
R
A
M
N
R
A
Rat
Rattus norvegicus
Q62915
909
103240
E832
L
K
V
L
R
T
A
E
F
P
P
F
V
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
T463
I
A
A
P
E
L
E
T
L
R
A
M
H
K
A
Chicken
Gallus gallus
Q5ZJ00
468
52501
T392
Q
T
L
K
I
V
R
T
A
E
L
S
P
F
I
Frog
Xenopus laevis
NP_001087762
532
59489
T455
V
G
A
P
D
F
Q
T
L
K
S
N
N
L
S
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
R498
I
E
R
L
R
E
T
R
R
N
A
K
V
I
S
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
T391
Q
T
M
K
V
L
R
T
A
D
F
G
P
L
M
Fruit Fly
Dros. melanogaster
Q24210
898
100893
E821
L
K
I
L
R
T
A
E
F
T
P
Y
V
V
F
Honey Bee
Apis mellifera
XP_391909
602
67965
Q525
I
A
A
P
G
M
E
Q
L
K
W
L
Y
D
L
Nematode Worm
Caenorhab. elegans
P54936
961
108794
E884
L
K
V
L
R
T
A
E
Y
S
P
F
V
V
F
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
D476
V
V
F
V
S
S
P
D
L
E
T
L
R
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
66.6
100
N.A.
93.3
0
N.A.
66.6
6.6
46.6
20
6.6
0
33.3
0
6.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
13.3
N.A.
86.6
6.6
80
26.6
6.6
13.3
46.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
54
0
0
0
20
0
14
0
47
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
0
7
0
7
0
0
0
7
0
% D
% Glu:
0
34
0
0
14
7
47
20
0
14
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
27
0
0
14
0
7
14
0
7
20
% F
% Gly:
0
7
0
0
7
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% H
% Ile:
54
0
7
0
7
0
0
0
0
0
0
0
0
14
7
% I
% Lys:
0
20
0
14
0
0
0
0
0
14
0
7
0
14
0
% K
% Leu:
20
0
7
27
0
20
0
0
60
0
7
14
0
14
14
% L
% Met:
0
0
7
0
0
7
0
0
0
0
0
40
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
7
34
0
0
% N
% Pro:
0
0
0
54
0
0
7
0
0
7
20
0
14
0
0
% P
% Gln:
14
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
27
0
14
7
7
40
0
0
7
27
0
% R
% Ser:
0
0
0
0
7
7
0
0
0
7
7
7
0
0
14
% S
% Thr:
0
14
0
0
0
20
7
60
0
7
7
0
0
0
0
% T
% Val:
14
7
14
7
7
7
0
0
0
0
0
0
27
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
7
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _